Eosinophilic Gastroenteritis: 10 Years Experience

Chuan‐Mo ‐M Lee, Chi‐Sin ‐S Changehien, Pang‐Chi ‐C Chen, Deng‐Yn ‐Y Lin, I‐Shyan ‐S Sheen, Chia‐Siu ‐S Wang, Dar‐In ‐I Tai, Shyr‐Ming ‐M Sheen‐Chen, Wei‐Jen ‐J Chen, Cheng‐Shyong ‐S Wu

Research output: Contribution to journalArticle

185 Citations (Scopus)

Abstract

Eight patients (five men, three women), mean age 36.9 ± 13.5 (17‐60) yr, were diagnosed to have eosinophilic gastroenteritis. The condition was proved in five patients by biopsies through endoscope, and in three, by operation. All had hypereosinophilia (absolute eosinophil count of 1,337‐21,787/cm3). According to Klein classification, two had mucosal disease, three had muscle layer disease, and three, subserosal disease. The most common symptoms were abdominal pain (100%), diarrhea (62.5%), vomiting (62.5%). and nausea (50%). Four patients (50%) had symptoms for more than 1 yr before diagnosis. Barium studies revealed mucosal edema and/or thickening of the small intestinal wall in three eases (including one case with ulceration), partial gastric outlet obstruction in one case, and narrowing of lumen of the terminal ileum in one case. Hypotonic duodenogram revealed double contour in one case. Ultrasound examination revealed thickening of the intestinal wall in two cases; computer tomography revealed thickening of the intestinal wall in one case. All patients were treated with steroid (40 mg/day for initial dose and relapse; 5–10 mg/day for maintenance). The symptoms subsided and the eosinophil counts returned to normal within 2 wk in seven patients and 1 month in one. Of six patients being followed up for 2–10 yr, one had remission, four needed small maintenance dose of steroid, and one suffered from relapse with intestinal perforation.

Original languageEnglish
Pages (from-to)70-74
Number of pages5
JournalThe American Journal of Gastroenterology
Volume88
Issue number1
DOIs
Publication statusPublished - Jan 1993
Externally publishedYes

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Eosinophils
Steroids
Gastric Outlet Obstruction
Intestinal Perforation
Recurrence
Endoscopes
Barium
Ileum
Nausea
Abdominal Pain
Vomiting
Eosinophilic enteropathy
Diarrhea
Edema
Tomography
Maintenance
Biopsy
Muscles

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Lee, CM. M., Changehien, CS. S., Chen, PC. C., Lin, DY. Y., Sheen, IS. S., Wang, CS. S., ... Wu, CS. S. (1993). Eosinophilic Gastroenteritis: 10 Years Experience. The American Journal of Gastroenterology, 88(1), 70-74. https://doi.org/10.1111/j.1572-0241.1993.tb07411.x

Eosinophilic Gastroenteritis : 10 Years Experience. / Lee, Chuan‐Mo ‐M; Changehien, Chi‐Sin ‐S; Chen, Pang‐Chi ‐C; Lin, Deng‐Yn ‐Y; Sheen, I‐Shyan ‐S; Wang, Chia‐Siu ‐S; Tai, Dar‐In ‐I; Sheen‐Chen, Shyr‐Ming ‐M; Chen, Wei‐Jen ‐J; Wu, Cheng‐Shyong ‐S.

In: The American Journal of Gastroenterology, Vol. 88, No. 1, 01.1993, p. 70-74.

Research output: Contribution to journalArticle

Lee, CMM, Changehien, CSS, Chen, PCC, Lin, DYY, Sheen, ISS, Wang, CSS, Tai, DII, Sheen‐Chen, SMM, Chen, WJJ & Wu, CSS 1993, 'Eosinophilic Gastroenteritis: 10 Years Experience', The American Journal of Gastroenterology, vol. 88, no. 1, pp. 70-74. https://doi.org/10.1111/j.1572-0241.1993.tb07411.x
Lee CMM, Changehien CSS, Chen PCC, Lin DYY, Sheen ISS, Wang CSS et al. Eosinophilic Gastroenteritis: 10 Years Experience. The American Journal of Gastroenterology. 1993 Jan;88(1):70-74. https://doi.org/10.1111/j.1572-0241.1993.tb07411.x
Lee, Chuan‐Mo ‐M ; Changehien, Chi‐Sin ‐S ; Chen, Pang‐Chi ‐C ; Lin, Deng‐Yn ‐Y ; Sheen, I‐Shyan ‐S ; Wang, Chia‐Siu ‐S ; Tai, Dar‐In ‐I ; Sheen‐Chen, Shyr‐Ming ‐M ; Chen, Wei‐Jen ‐J ; Wu, Cheng‐Shyong ‐S. / Eosinophilic Gastroenteritis : 10 Years Experience. In: The American Journal of Gastroenterology. 1993 ; Vol. 88, No. 1. pp. 70-74.
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