Enhancing bright-field image of microorganisms by local plasmon of Ag nanoparticle array

Hui Hsin Hsiao, Po Chun Yeh, Huai Hsien Wang, Tian You Cheng, Hung Chun Chang, Yuh Lin Wang, Juen Kai Wang

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Inspecting biological cells with bright-field light microscopy often engenders a challenge, owing to their optical transparency. We show that imaging contrast can be greatly enhanced as yeast cells are placed on a silver nano-particle array. Its near- and far-field traits, revealed by electrodynamic simulations, illustrate that the enhancement is attributed to the sensitivity of its plasmonic characteristics to the attached cells. This study demonstrates that the silver nanoparticle array can serve as the agent for concurrently enhancing Raman scattering and imaging contrast of microorganisms for identification and examination.

Original languageEnglish
Pages (from-to)1173-1176
Number of pages4
JournalOptics Letters
Volume39
Issue number5
DOIs
Publication statusPublished - Mar 1 2014
Externally publishedYes

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ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Hsiao, H. H., Yeh, P. C., Wang, H. H., Cheng, T. Y., Chang, H. C., Wang, Y. L., & Wang, J. K. (2014). Enhancing bright-field image of microorganisms by local plasmon of Ag nanoparticle array. Optics Letters, 39(5), 1173-1176. https://doi.org/10.1364/OL.39.001173