Abstract
Dibutyryl adenosine cyclic 3', 5'-monophosphate (10'7-10-6 M) augmented the response (transformation, DNA synthesis, and mitosis)of normal human lymphocytes to antigenic or mitogenic stimulation. Incontrast, the response of lymphocytes from patients with lymphocyticleukemia was not enhanced. Higher concentrations (10-6-10-5 M) wereinhibitory with both normal and leukemic lymphocytes.—J Nat CancerInst 47: 91-94, 1971.
| Original language | English |
|---|---|
| Pages (from-to) | 91-94 |
| Number of pages | 4 |
| Journal | Journal of the National Cancer Institute |
| Volume | 47 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 1971 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Enhanced transformation of human immunocompetent cells by dibutyryl adenosine cyclic 3', 5'-monophosphate 1. / Gallo, Robert C.; Whang-Peng, Jacqueline.
In: Journal of the National Cancer Institute, Vol. 47, No. 1, 01.01.1971, p. 91-94.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Enhanced transformation of human immunocompetent cells by dibutyryl adenosine cyclic 3', 5'-monophosphate 1
AU - Gallo, Robert C.
AU - Whang-Peng, Jacqueline
PY - 1971/1/1
Y1 - 1971/1/1
N2 - Dibutyryl adenosine cyclic 3', 5'-monophosphate (10'7-10-6 M) augmented the response (transformation, DNA synthesis, and mitosis)of normal human lymphocytes to antigenic or mitogenic stimulation. Incontrast, the response of lymphocytes from patients with lymphocyticleukemia was not enhanced. Higher concentrations (10-6-10-5 M) wereinhibitory with both normal and leukemic lymphocytes.—J Nat CancerInst 47: 91-94, 1971.
AB - Dibutyryl adenosine cyclic 3', 5'-monophosphate (10'7-10-6 M) augmented the response (transformation, DNA synthesis, and mitosis)of normal human lymphocytes to antigenic or mitogenic stimulation. Incontrast, the response of lymphocytes from patients with lymphocyticleukemia was not enhanced. Higher concentrations (10-6-10-5 M) wereinhibitory with both normal and leukemic lymphocytes.—J Nat CancerInst 47: 91-94, 1971.
UR - http://www.scopus.com/inward/record.url?scp=0015094067&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015094067&partnerID=8YFLogxK
U2 - 10.1093/jnci/47.1.91
DO - 10.1093/jnci/47.1.91
M3 - Article
C2 - 4328198
AN - SCOPUS:0015094067
VL - 47
SP - 91
EP - 94
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 1
ER -