Endoscopic injection of alcohol to stop peptic ulcer hemorrhage: Experience with 115 cases

Hwai Jeng Lin, Fa Yauh Lee, Chen Hsen Lee, Shou Dong Lee

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.

Original languageEnglish
Pages (from-to)376-379
Number of pages4
JournalJournal of Clinical Gastroenterology
Volume13
Issue number4
Publication statusPublished - 1991
Externally publishedYes

Keywords

  • Endoscopic injection
  • Hemostasis
  • Peptic ulcer hemorrhage
  • Shock

ASJC Scopus subject areas

  • Gastroenterology

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