Endoscopic injection of alcohol to stop peptic ulcer hemorrhage

Experience with 115 cases

Hwai Jeng Lin, Fa Yauh Lee, Chen Hsen Lee, Shou Dong Lee

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.

Original languageEnglish
Pages (from-to)376-379
Number of pages4
JournalJournal of Clinical Gastroenterology
Volume13
Issue number4
Publication statusPublished - 1991
Externally publishedYes

Fingerprint

Peptic Ulcer Hemorrhage
Alcohols
Injections
Hemorrhage
Sex Ratio
Blood Volume
Shock
Hospitalization
Therapeutics

Keywords

  • Endoscopic injection
  • Hemostasis
  • Peptic ulcer hemorrhage
  • Shock

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Endoscopic injection of alcohol to stop peptic ulcer hemorrhage : Experience with 115 cases. / Lin, Hwai Jeng; Lee, Fa Yauh; Lee, Chen Hsen; Lee, Shou Dong.

In: Journal of Clinical Gastroenterology, Vol. 13, No. 4, 1991, p. 376-379.

Research output: Contribution to journalArticle

Lin, Hwai Jeng ; Lee, Fa Yauh ; Lee, Chen Hsen ; Lee, Shou Dong. / Endoscopic injection of alcohol to stop peptic ulcer hemorrhage : Experience with 115 cases. In: Journal of Clinical Gastroenterology. 1991 ; Vol. 13, No. 4. pp. 376-379.
@article{67604748745e437e88ac05d20dfdb5d9,
title = "Endoscopic injection of alcohol to stop peptic ulcer hemorrhage: Experience with 115 cases",
abstract = "In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9{\%}) were in shock before endoscopic injection. Thirty-three (28.7{\%}) had spurting hemorrhage, 31 (27{\%}) oozing hemorrhage, and 51 (44.3{\%}) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80{\%}). Rebleeding episodes occurred in 7 patients (7.6{\%}) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5{\%}) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.",
keywords = "Endoscopic injection, Hemostasis, Peptic ulcer hemorrhage, Shock",
author = "Lin, {Hwai Jeng} and Lee, {Fa Yauh} and Lee, {Chen Hsen} and Lee, {Shou Dong}",
year = "1991",
language = "English",
volume = "13",
pages = "376--379",
journal = "Journal of Clinical Gastroenterology",
issn = "0192-0790",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Endoscopic injection of alcohol to stop peptic ulcer hemorrhage

T2 - Experience with 115 cases

AU - Lin, Hwai Jeng

AU - Lee, Fa Yauh

AU - Lee, Chen Hsen

AU - Lee, Shou Dong

PY - 1991

Y1 - 1991

N2 - In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.

AB - In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 ± 1.5 years (mean ± SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 ± 0.6 days (mean ± SEM). The total volume of blood transfused was 1450 ± 192 ml (mean ± SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.

KW - Endoscopic injection

KW - Hemostasis

KW - Peptic ulcer hemorrhage

KW - Shock

UR - http://www.scopus.com/inward/record.url?scp=0025787356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025787356&partnerID=8YFLogxK

M3 - Article

VL - 13

SP - 376

EP - 379

JO - Journal of Clinical Gastroenterology

JF - Journal of Clinical Gastroenterology

SN - 0192-0790

IS - 4

ER -