Emergence of a strain of methicillin-resistant Staphylococcus aureus with decreased susceptibility to vancomycin 7 months after treatment with glycopeptide antibiotics

Cheng Len Sy, Susan Shin Jung Lee, Kuan Sheng Wu, Hung Chin Tsai, Yung Ching Liu, Yao Shen Chen

Research output: Contribution to journalArticle

1 Citation (Scopus)


This case report describes a methicillin-resistant Staphylococcus aureus isolated repeatedly from the blood of a patient with community-acquired endocarditis who developed a four-fold increase in the minimal inhibitory concentration of vancomycin and daptomycin 7 months after his last exposure to glycopeptide antibiotics. This is contrary to the expected situation in which antimicrobial resistance tends to decrease after a patient is no longer exposed to vancomycin.

Original languageEnglish
Pages (from-to)142-145
Number of pages4
JournalJournal of Microbiology, Immunology and Infection
Issue number1
Publication statusPublished - Feb 1 2016



  • Daptomycin
  • Glycopeptide
  • Resistance
  • Staphylococcus aureus
  • Vancomycin

ASJC Scopus subject areas

  • Microbiology (medical)
  • Immunology and Allergy
  • Immunology and Microbiology(all)
  • Infectious Diseases

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