Electrophysiological changes in lipaemia retinalis

Chao Kung Lu, Shih Jen Chen, Dau Ming Niu, Chia Chen Tsai, Fenq Lih Lee, Wen-Ming Hsu

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

PURPOSE: To report the electrophysiologic findings in a patient with lipaemia retinalis. DESIGN: Observational case report. METHODS: An 11-year-old girl with diabetes had hyperlipidemia and presented for ophthalmologic consultation. Fundus examinations revealed milky discoloration of retinal vessels in both eyes. Laboratory testing disclosed hyperglycemia and markedly elevated level of triglycerides and cholesterol. Although the visual acuity was not affected, the electroretinograms showed decrease amplitudes of a- and b-wave in both cone and rod responses. RESULTS: After correction of blood sugar and lipids with insulin and diet control, the lipaemia retinalis resolved, and the impaired ERG response reversed within 1 week. CONCLUSIONS: Lipaemia retinalis usually resolves rapidly without visual impairment after correction of hyperlipidemia. The reversible deficits of electroretinogram response in lipaemia retinalis are reported for the first time. High level of triglycerides or cholesterol or both may impair retinal function. The mechanism of an impaired electroretinogram remained speculative.

Original languageEnglish
Pages (from-to)1142-1145
Number of pages4
JournalAmerican Journal of Ophthalmology
Volume139
Issue number6
DOIs
Publication statusPublished - Jun 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology

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