Elastinolytic activity in the rat aortic smooth muscle cells in culture

J. Nakao, W. C. Chang, S. Murota, H. Orimo

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Elastinolytic activity was examined in cultured rat aortic smooth muscle cells, using Congo Red elastin as a substrate. Elastinolytic activity was demonstrated in the soluble fraction of sonicated smooth muscle cells, with an optimal pH around 10.0. The soluble fraction also showed elastase-like esterolytic activity against the synthetic substrate, N-succinyl-trialanyl-paranitroanilide.

Original languageEnglish
Pages (from-to)539-544
Number of pages6
JournalAtherosclerosis
Volume36
Issue number4
Publication statusPublished - 1980
Externally publishedYes

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Smooth Muscle Myocytes
Cell Culture Techniques
Congo Red
Elastin
Pancreatic Elastase

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Elastinolytic activity in the rat aortic smooth muscle cells in culture. / Nakao, J.; Chang, W. C.; Murota, S.; Orimo, H.

In: Atherosclerosis, Vol. 36, No. 4, 1980, p. 539-544.

Research output: Contribution to journalArticle

Nakao, J, Chang, WC, Murota, S & Orimo, H 1980, 'Elastinolytic activity in the rat aortic smooth muscle cells in culture', Atherosclerosis, vol. 36, no. 4, pp. 539-544.
Nakao, J. ; Chang, W. C. ; Murota, S. ; Orimo, H. / Elastinolytic activity in the rat aortic smooth muscle cells in culture. In: Atherosclerosis. 1980 ; Vol. 36, No. 4. pp. 539-544.
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