Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas

Wei Min Liu, Peng Hui Wang, Chun-Shan Chou, Wun Long Tang, I. Te Wang, Chii Ruey Tzeng

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Objective: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone. Design: Controlled, nonrandomized clinical study. Setting: University-affiliated tertiary care referral center. Patient(s): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus. Fifty-two patients (63.4%) underwent laparoscopic uterine artery occlusion and subsequent minilaparotomy and myomectomy (group I) and 30 patients (36.6%) underwent myomectomy alone (group II). Intervention(s): Occlusion of the uterine arteries was performed with a laparoscopic approach before minilaparotomy and myomectomy. Main Outcome Measure(s): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups. Results: The average blood loss was 125 ± 72.6 and 550 ± 394.8 mL in groups I and II, respectively. The recurrence rate of uterine myomas was 5.8% (3 of 52) in group I and 36.7% (11 of 30) in group II during an average follow-up period of 42.5 months. Of the sexually active patients who did not use contraception, 19.2% (5 of 26) and 22.4% (4 of 18) became pregnant in groups I and II, respectively (no statistical significance). Conclusion(s): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.

Original languageEnglish
Pages (from-to)356-361
Number of pages6
JournalFertility and Sterility
Volume87
Issue number2
DOIs
Publication statusPublished - Feb 2007

Fingerprint

Uterine Myomectomy
Uterine Artery
Myoma
Laparotomy
Tertiary Care Centers
Therapeutics
Recurrence
Birth Rate
Contraception
Blood Transfusion
Uterus
Fever
Outcome Assessment (Health Care)
Morbidity

Keywords

  • fertility
  • Laparoscopic uterine artery occlusion
  • myomectomy
  • recurrent uterine myomas

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas. / Liu, Wei Min; Wang, Peng Hui; Chou, Chun-Shan; Tang, Wun Long; Wang, I. Te; Tzeng, Chii Ruey.

In: Fertility and Sterility, Vol. 87, No. 2, 02.2007, p. 356-361.

Research output: Contribution to journalArticle

@article{bb8907c9976b4f9388e4dc8d50c76ebc,
title = "Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas",
abstract = "Objective: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone. Design: Controlled, nonrandomized clinical study. Setting: University-affiliated tertiary care referral center. Patient(s): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus. Fifty-two patients (63.4{\%}) underwent laparoscopic uterine artery occlusion and subsequent minilaparotomy and myomectomy (group I) and 30 patients (36.6{\%}) underwent myomectomy alone (group II). Intervention(s): Occlusion of the uterine arteries was performed with a laparoscopic approach before minilaparotomy and myomectomy. Main Outcome Measure(s): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups. Results: The average blood loss was 125 ± 72.6 and 550 ± 394.8 mL in groups I and II, respectively. The recurrence rate of uterine myomas was 5.8{\%} (3 of 52) in group I and 36.7{\%} (11 of 30) in group II during an average follow-up period of 42.5 months. Of the sexually active patients who did not use contraception, 19.2{\%} (5 of 26) and 22.4{\%} (4 of 18) became pregnant in groups I and II, respectively (no statistical significance). Conclusion(s): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.",
keywords = "fertility, Laparoscopic uterine artery occlusion, myomectomy, recurrent uterine myomas",
author = "Liu, {Wei Min} and Wang, {Peng Hui} and Chun-Shan Chou and Tang, {Wun Long} and Wang, {I. Te} and Tzeng, {Chii Ruey}",
year = "2007",
month = "2",
doi = "10.1016/j.fertnstert.2006.07.1497",
language = "English",
volume = "87",
pages = "356--361",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas

AU - Liu, Wei Min

AU - Wang, Peng Hui

AU - Chou, Chun-Shan

AU - Tang, Wun Long

AU - Wang, I. Te

AU - Tzeng, Chii Ruey

PY - 2007/2

Y1 - 2007/2

N2 - Objective: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone. Design: Controlled, nonrandomized clinical study. Setting: University-affiliated tertiary care referral center. Patient(s): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus. Fifty-two patients (63.4%) underwent laparoscopic uterine artery occlusion and subsequent minilaparotomy and myomectomy (group I) and 30 patients (36.6%) underwent myomectomy alone (group II). Intervention(s): Occlusion of the uterine arteries was performed with a laparoscopic approach before minilaparotomy and myomectomy. Main Outcome Measure(s): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups. Results: The average blood loss was 125 ± 72.6 and 550 ± 394.8 mL in groups I and II, respectively. The recurrence rate of uterine myomas was 5.8% (3 of 52) in group I and 36.7% (11 of 30) in group II during an average follow-up period of 42.5 months. Of the sexually active patients who did not use contraception, 19.2% (5 of 26) and 22.4% (4 of 18) became pregnant in groups I and II, respectively (no statistical significance). Conclusion(s): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.

AB - Objective: To evaluate the therapeutic efficacy of laparoscopic uterine artery occlusion combined with myomectomy through a minilaparotomy in the treatment of recurrent uterine myomas, compared with myomectomy alone. Design: Controlled, nonrandomized clinical study. Setting: University-affiliated tertiary care referral center. Patient(s): Eighty-two women with symptomatic, recurrent myomas warranting surgical treatment, who expressed a strong desire to retain their uterus. Fifty-two patients (63.4%) underwent laparoscopic uterine artery occlusion and subsequent minilaparotomy and myomectomy (group I) and 30 patients (36.6%) underwent myomectomy alone (group II). Intervention(s): Occlusion of the uterine arteries was performed with a laparoscopic approach before minilaparotomy and myomectomy. Main Outcome Measure(s): The efficacy of combined laparoscopic uterine artery occlusion and myomectomy via minilaparotomy in the treatment of recurrent uterine myomas was measured by comparing blood loss, need for blood transfusion, postoperative febrile morbidity, recurrence rate of the uterine myomas, and fertility rate in the treatment (group I) and control (group II) groups. Results: The average blood loss was 125 ± 72.6 and 550 ± 394.8 mL in groups I and II, respectively. The recurrence rate of uterine myomas was 5.8% (3 of 52) in group I and 36.7% (11 of 30) in group II during an average follow-up period of 42.5 months. Of the sexually active patients who did not use contraception, 19.2% (5 of 26) and 22.4% (4 of 18) became pregnant in groups I and II, respectively (no statistical significance). Conclusion(s): This study has demonstrated the superiority of laparoscopic uterine artery occlusion when combined with repeat myomectomy in treating recurrent symptomatic myomas.

KW - fertility

KW - Laparoscopic uterine artery occlusion

KW - myomectomy

KW - recurrent uterine myomas

UR - http://www.scopus.com/inward/record.url?scp=33846602811&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33846602811&partnerID=8YFLogxK

U2 - 10.1016/j.fertnstert.2006.07.1497

DO - 10.1016/j.fertnstert.2006.07.1497

M3 - Article

C2 - 17069812

AN - SCOPUS:33846602811

VL - 87

SP - 356

EP - 361

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 2

ER -