Effects on the Oxidation-of Human Low-density Lipoprotein and Antioxidant Activities of Tai-Long-57 Sweet Potato Vines

劉 麗雲(Li-Yun Liu), 劉 佳苓(Chia-Ling Liu), 陳 永怡(Yung-Yi Chen), 簡 怡雯(Yi-Wen Chien)

Research output: Contribution to journalArticle

Abstract

Antioxidant activities of sweet potato vines and their corresponding in vitro effects on the oxidation of human low-density lipoprotein (LDL) were studied in this subject. The results showed that total phenol and flavonoid contents in 80% methanol extracts were greater than their respective counterparts in water extracts. The effectiveness of 1,1-diphenyl-s-picryl-hydrazyl (DPPH) scavenging activity and Fe^(2+)-chelating activities of sweet potato vines of 80% methanol extracts were higher than those of water extract. The DPPH IC_(50) values of 80% methanol extracts and water extracts were 4.91 and 11.68 mg/mL, respectively; and the Fe^(2+)-chelating activities of vines 80% methanol extract were greater than those of water extract by 3.36~3.97 folds. The 80% methanol extract at 200 μg/mL decreased 83.3% (p<0.01) thiobarbituric acid-reactive substances (TBARS) of human LDL, and extended the lag time of human LDL from 1 to 4 h at 20 μg/mL. These findings suggest that 80% methanol extract of sweet potato vines has significantly inhibitory activities against copper ion-induced LDL oxidation.
Original languageEnglish
Pages (from-to)1-9
Number of pages9
Journal中華生質能源學會會誌
Volume34
Issue number1&2
Publication statusPublished - 2015

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low density lipoprotein
sweet potatoes
vines
antioxidant activity
oxidation
extracts
methanol
biphenyl
water
thiobarbituric acid-reactive substances
phenol
inhibitory concentration 50
flavonoids
copper
ions

Keywords

  • Sweet potato vines
  • Antioxidant activities
  • Human LDL
  • 1,1-Diphenyl-s-picrylhydrazyl (DPPH)
  • Low-density lipoprotein (LDL)
  • Thiobarbituric acid-reactive substances (TBARS)
  • 甘薯藤
  • 抗氧化活性
  • 人類低密度脂蛋白
  • DPPH自由基
  • 硫巴比妥酸

Cite this

Effects on the Oxidation-of Human Low-density Lipoprotein and Antioxidant Activities of Tai-Long-57 Sweet Potato Vines. / 劉麗雲(Li-Yun Liu); 劉佳苓(Chia-Ling Liu); 陳永怡(Yung-Yi Chen); 簡怡雯(Yi-Wen Chien).

In: 中華生質能源學會會誌, Vol. 34, No. 1&2, 2015, p. 1-9.

Research output: Contribution to journalArticle

劉麗雲(Li-Yun Liu) ; 劉佳苓(Chia-Ling Liu) ; 陳永怡(Yung-Yi Chen) ; 簡怡雯(Yi-Wen Chien). / Effects on the Oxidation-of Human Low-density Lipoprotein and Antioxidant Activities of Tai-Long-57 Sweet Potato Vines. In: 中華生質能源學會會誌. 2015 ; Vol. 34, No. 1&2. pp. 1-9.
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AU - 劉, 麗雲(Li-Yun Liu)

AU - 劉, 佳苓(Chia-Ling Liu)

AU - 陳, 永怡(Yung-Yi Chen)

AU - 簡, 怡雯(Yi-Wen Chien)

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N2 - Antioxidant activities of sweet potato vines and their corresponding in vitro effects on the oxidation of human low-density lipoprotein (LDL) were studied in this subject. The results showed that total phenol and flavonoid contents in 80% methanol extracts were greater than their respective counterparts in water extracts. The effectiveness of 1,1-diphenyl-s-picryl-hydrazyl (DPPH) scavenging activity and Fe^(2+)-chelating activities of sweet potato vines of 80% methanol extracts were higher than those of water extract. The DPPH IC_(50) values of 80% methanol extracts and water extracts were 4.91 and 11.68 mg/mL, respectively; and the Fe^(2+)-chelating activities of vines 80% methanol extract were greater than those of water extract by 3.36~3.97 folds. The 80% methanol extract at 200 μg/mL decreased 83.3% (p<0.01) thiobarbituric acid-reactive substances (TBARS) of human LDL, and extended the lag time of human LDL from 1 to 4 h at 20 μg/mL. These findings suggest that 80% methanol extract of sweet potato vines has significantly inhibitory activities against copper ion-induced LDL oxidation.

AB - Antioxidant activities of sweet potato vines and their corresponding in vitro effects on the oxidation of human low-density lipoprotein (LDL) were studied in this subject. The results showed that total phenol and flavonoid contents in 80% methanol extracts were greater than their respective counterparts in water extracts. The effectiveness of 1,1-diphenyl-s-picryl-hydrazyl (DPPH) scavenging activity and Fe^(2+)-chelating activities of sweet potato vines of 80% methanol extracts were higher than those of water extract. The DPPH IC_(50) values of 80% methanol extracts and water extracts were 4.91 and 11.68 mg/mL, respectively; and the Fe^(2+)-chelating activities of vines 80% methanol extract were greater than those of water extract by 3.36~3.97 folds. The 80% methanol extract at 200 μg/mL decreased 83.3% (p<0.01) thiobarbituric acid-reactive substances (TBARS) of human LDL, and extended the lag time of human LDL from 1 to 4 h at 20 μg/mL. These findings suggest that 80% methanol extract of sweet potato vines has significantly inhibitory activities against copper ion-induced LDL oxidation.

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