Effects of Tribochemistry of Synovial Fluids on the Performance of Unicondylar Knee Arthroplasty - Development of the Testing Model

Chih Hung Chang, Hsu-Wei Fang, Hwa Chang Liu, Feng Huei Lin, Wei Ming Lee, Huei Ting Huang, Wun Hsing Lee, Chiang San Chen

Research output: Contribution to journalArticle


Partial joint arthroplasty surgeries have been widely applied to the patients with unicondylar knee joint osteoarthritis. Degeneration in the opposite compartment is a common cause of failure after unicompartmental arthroplasty. It is suggested that the decreased synovial fluid lubrication might be related to the cartilage damage. In the situations of partial joint arthroplasty, the influence of chemically conformed fluids released from the arthroplasty implant interface on the lubricating ability of the natural cartilage becomes one of the most critical issues. Once the association of the tribochemistry of biological lubricants due to the arthroplasty implant articulation and the degeneration of the cartilage is identified, further development can be made to enhance the durability of partial joint arthroplasty. In this study, in-vitro testing procedures have been successfully developed to investigate the effects of tribochemical reactions of biological lubricants on the friction change of articular cartilages. The results indicated that the lubricating ability for cartilages deteriorates after of the biological lubricants were articulated by ultra-high molecular weight polyethylene (UHMWPE) and stainless steel
Original languageEnglish
JournalJournal of Orthopaedic Surgery
Publication statusPublished - 2006
Externally publishedYes


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