Effects of soy components on blood and liver lipids in rats fed high-cholesterol diets

Ching Yi Lin; Cheng Yu Tsai; Shyh Hsiang Lin

Effects of soy components on blood and liver lipids in rats fed high-cholesterol diets

Ching Yi Lin, Cheng Yu Tsai, Shyh Hsiang Lin

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: To assess the effects of soy protein, isoflavone, and saponin on liver and blood lipid in rats that consumed high-cholesterol diets. Methods: High-cholesterol diets (1%) with or without soy material were fed to 6-wk-old male Sprague-Dawley rats for 8 wk. Blood lipids, liver lipids, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) levels were measured. The in vitro bile acid-binding ability of soy materials was analyzed. Results: The results of in vitro studies showed that soy protein isolate had a significantly higher bile acid-binding ability (8.4±0.8%) than soy saponin (3.1±0.7%) and isoflavone (1.3±0.4%, P

Original language	English
Pages (from-to)	5549-5552
Number of pages	4
Journal	World Journal of Gastroenterology
Volume	11
Issue number	35
Publication status	Published - Sep 21 2005

Keywords

Cholesterol
Isoflavone
Saponin
Soy
Triglyceride

ASJC Scopus subject areas

Gastroenterology

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title = "Effects of soy components on blood and liver lipids in rats fed high-cholesterol diets",

abstract = "Aim: To assess the effects of soy protein, isoflavone, and saponin on liver and blood lipid in rats that consumed high-cholesterol diets. Methods: High-cholesterol diets (1%) with or without soy material were fed to 6-wk-old male Sprague-Dawley rats for 8 wk. Blood lipids, liver lipids, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) levels were measured. The in vitro bile acid-binding ability of soy materials was analyzed. Results: The results of in vitro studies showed that soy protein isolate had a significantly higher bile acid-binding ability (8.4±0.8%) than soy saponin (3.1±0.7%) and isoflavone (1.3±0.4%, P",

keywords = "Cholesterol, Isoflavone, Saponin, Soy, Triglyceride",

author = "Lin, {Ching Yi} and Tsai, {Cheng Yu} and Lin, {Shyh Hsiang}",

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AU - Lin, Ching Yi

AU - Tsai, Cheng Yu

AU - Lin, Shyh Hsiang

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Y1 - 2005/9/21

N2 - Aim: To assess the effects of soy protein, isoflavone, and saponin on liver and blood lipid in rats that consumed high-cholesterol diets. Methods: High-cholesterol diets (1%) with or without soy material were fed to 6-wk-old male Sprague-Dawley rats for 8 wk. Blood lipids, liver lipids, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) levels were measured. The in vitro bile acid-binding ability of soy materials was analyzed. Results: The results of in vitro studies showed that soy protein isolate had a significantly higher bile acid-binding ability (8.4±0.8%) than soy saponin (3.1±0.7%) and isoflavone (1.3±0.4%, P

AB - Aim: To assess the effects of soy protein, isoflavone, and saponin on liver and blood lipid in rats that consumed high-cholesterol diets. Methods: High-cholesterol diets (1%) with or without soy material were fed to 6-wk-old male Sprague-Dawley rats for 8 wk. Blood lipids, liver lipids, glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) levels were measured. The in vitro bile acid-binding ability of soy materials was analyzed. Results: The results of in vitro studies showed that soy protein isolate had a significantly higher bile acid-binding ability (8.4±0.8%) than soy saponin (3.1±0.7%) and isoflavone (1.3±0.4%, P

KW - Cholesterol

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KW - Saponin

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KW - Triglyceride

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