Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients

Ming Hoang Lai, Yi Ting Chen, Ya Yen Chen, Jui Hung Chang, Hsing Hsien Cheng

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

The aim of this study was to investigate the influence of rice bran consumption on plasma lipids and insulin resistance in patients with type 2 diabetes. Thirty-five patients with type 2 diabetes were randomly assigned to a placebo group or a rice bran oil group. The placebo group consumed 250 mL soybean oil-modified milk (18 g soybean oil) daily for 5 weeks, and the rice bran oil group consumed 250 mL rice bran oil modified milk (18 g rice bran oil) daily for 5 weeks. At week 0 and week 5, anthropometric measurements, hematology tests, and an oral-glucose-tolerance test were conducted. The results showed that the homeostasis model assessment index of insulin resistance, the area under the curve for postprandial serum insulin, and serum low-density- lipoprotein cholesterol concentrations increased significantly in the placebo group. In the rice bran oil group, fasting and 2-h post-prandial blood glucose concentrations and the area under the curve for postprandial plasma glucose increased significantly; however, total serum cholesterol and low-density-lipoprotein cholesterol concentrations decreased significantly. However, the homeostasis model assessment index of insulin resistance was not significantly different. Consumption of 18 g rice bran oil modified milk daily for 5 weeks significantly decreased total serum cholesterol concen-trations and tended to decrease low-density-lipoprotein cholesterol concentrations in patients with type 2 diabetes. However, no significant influence on insulin resistance was observed.

Original languageEnglish
Pages (from-to)15-18
Number of pages4
JournalJournal of Clinical Biochemistry and Nutrition
Volume51
Issue number1
DOIs
Publication statusPublished - 2012

Fingerprint

Medical problems
Type 2 Diabetes Mellitus
Insulin Resistance
Blood
Insulin
Lipids
LDL Cholesterol
Soybean Oil
Milk
Placebos
Serum
Area Under Curve
Homeostasis
Cholesterol
Plasmas
Glucose
Hematology
Glucose Tolerance Test
Meals
Blood Glucose

Keywords

  • Blood lipids
  • Rice bran oil
  • Type 2 diabetes

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients. / Lai, Ming Hoang; Chen, Yi Ting; Chen, Ya Yen; Chang, Jui Hung; Cheng, Hsing Hsien.

In: Journal of Clinical Biochemistry and Nutrition, Vol. 51, No. 1, 2012, p. 15-18.

Research output: Contribution to journalArticle

Lai, Ming Hoang ; Chen, Yi Ting ; Chen, Ya Yen ; Chang, Jui Hung ; Cheng, Hsing Hsien. / Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients. In: Journal of Clinical Biochemistry and Nutrition. 2012 ; Vol. 51, No. 1. pp. 15-18.
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