紅麴粉末對倉鼠體內CoQ10、維生素E及低密度脂蛋白脂肪酸的影響

Translated title of the contribution: Effects of Monascus rice powder on coenzyme Q10, vitamin E, and fatty acids of low-density lipoprotein in hamster

Meng Jyh Shieh, Shih Yi Huang, Hui Ting Yang, Pei Yang Liu, Hsin Chien, Yao Ling Liu, Ming-Che Hsieh

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2 Citations (Scopus)

Abstract

The aim of this study was to assess the effect of the Monascus rice powder on coenzyme Q10 (CoQ10), vitamin E, and plasma low-density lipoprotein (LDL) fatty acid profiles in male hamsters. Seventytwo male hamsters (110 g) were divided into six treatment groups (C, control diet; L, low-dose 0.5% Monascus rice powder diet; H, high-dose 4% Monascus rice powder diet; CE, LE, and HE, are the C, L, and H group each with the addition of 0.3% vitamin E). After a 4-week experimental period, blood and liver samples were taken for cholesterol, triglycerides, malondialdehyde (MDA), vitamin E, and CoQ10 analysis. Results indicated that Monascus rice powder could significantly lower plasma cholesterol level, the LDL-C/HDL-C ratio, and plasma triglyceride, hepatic total cholesterol, and triglyceride levels. In addition, Monascus rice powder also decreased both the linoleic acid/arachidonic acid and PUFA/MUFA ratios in the low-ensity lipoprotein. However, Monascus rice powder reduced the plasma vitamin E content, the vitamin E/LDL-C ratio but hepatic vitamin E significantly increased. Vitamin E but not Monascus rice powder inhibited hepatic MDA production. The content of hamster hepatic CoQ10 significantly decreased with Monascus rice powder, whereas the CoQ10/cholesterol ratio increased. In summary, the antioxidative effect of Monascus rice powder was affected by many factors. Monascus rice powder not only decreased the hepatic levels of CoQ10 and vitamin E but decreased the cholesterol content simultaneously, with the result that it had no effect on antioxidative activity.

Original languageTraditional Chinese
Pages (from-to)230-239
Number of pages10
JournalNutritional Sciences Journal
Volume26
Issue number4
Publication statusPublished - 2001

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Keywords

  • Coenzyme Q
  • LDL fatty acid profile
  • Monascus rice powder
  • Vitamin E

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

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