Effects of long-term ethanol consumption on jejunal lipase and disaccharidase activities in male and female rats

Chi Chang Huang, Jiun Rong Chen, Chieh Chung Liu, Kung Tung Chen, Ming Jer Shieh, Suh Ching Yang

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Abstract

Aim: To study the effect of long-term ethanol consumption on jejunal lipase and disaccharidase (sucrase, maltase, and lactase) activities in rats and its gender difference. Methods: Age-matched male and female Wistar rats were fed control or ethanol-containing liquid diets for 12 wk following the Lieber-DeCarli model. According to both the plasma aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities, 40 rats were divided into four groups as follows: male control group (MC), male ethanol group (ME), female control group (FC), and female ethanol group (FE). Results: After ethanol feeding for 12 wk, the results revealed that plasma AST and ALT activities of group ME were significantly increased by 58% and 92%, respectively, than those of group MC (P

Original languageEnglish
Pages (from-to)2603-2608
Number of pages6
JournalWorld Journal of Gastroenterology
Volume11
Issue number17
Publication statusPublished - May 7 2005

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Keywords

  • Disaccharidase
  • Ethanol consumption
  • Gender difference
  • Jejunal lipase
  • Rats

ASJC Scopus subject areas

  • Gastroenterology

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