Effects of hydroxyapatite dosage on mechanical and biological behaviors of polylactic acid composite materials

Po Liang Lin, Hsu Wei Fang, Tiffany Tseng, Wun Hsing Lee

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Due to the widespread use of bioresorbable polylactic acid (PLA) based materials in biomedical applications, there is an increasing need to obtain independent control of key properties such as mechanical strength, degradation rate and bioactivity in order to further enhance the performance of the PLA based medical implants. Because PLA composites containing hydroxyapatite (HAp) particles can augment cell growth and mechanical properties, in this present study, the effects of HAp dosages on various mechanical strengths and cell proliferation of PLA composites were further investigated. The information resulting from this study can assist in the optimizing of PLA composite formulas for specific medical applications.

Original languageEnglish
Pages (from-to)3009-3013
Number of pages5
JournalMaterials Letters
Volume61
Issue number14-15
DOIs
Publication statusPublished - Jun 1 2007
Externally publishedYes

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Keywords

  • Cell proliferation
  • Composite
  • Hydroxyapatite
  • Mechanical strength
  • Polylactic acid

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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