Effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer

Jane Chen Jui Chao, Huei Chen Hung, Sheng-Hsuan Chen, Chia Lang Fang

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8 Citations (Scopus)

Abstract

Aim: To investigate the effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer. Methods: Sprague-Dawley rats were randomly divided into four groups: sham operation without ginkgo, sham operation with ginkgo, duodenal ulcer without ginkgo, and duodenal ulcer with ginkgo. Rats with duodenal ulcer were induced by 500 mL/L acetic acid. Rats with ginkgo were intravenously injected with Ginkgo biloba extract from the tail at a dose of 0.5 mg/(kg.d) for 7 and 14 days. Results: Pathological result showed that duodenal ulcer rats with ginkgo improved mucosal healing and inflammation compared with those without ginkgo after 7 d treatment. After 14 d treatment, duodenal ulcer rats with ginkgo significantly increased weight gain (34.0±4.5 g versus 24.5±9.5 g, P2 concentration significantly increased by 129% (P

Original languageEnglish
Pages (from-to)560-566
Number of pages7
JournalWorld Journal of Gastroenterology
Volume10
Issue number4
Publication statusPublished - Feb 15 2004

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Ginkgo biloba
Duodenal Ulcer
Acetic Acid
Weight Gain
Sprague Dawley Rats
Tail
Inflammation

ASJC Scopus subject areas

  • Gastroenterology

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Effects of Ginkgo biloba extract on cytoprotective factors in rats with duodenal ulcer. / Chao, Jane Chen Jui; Hung, Huei Chen; Chen, Sheng-Hsuan; Fang, Chia Lang.

In: World Journal of Gastroenterology, Vol. 10, No. 4, 15.02.2004, p. 560-566.

Research output: Contribution to journalArticle

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