Effects of endurance exercise training on risk components for metabolic syndrome, interleukin-6, and the exercise capacity of postmenopausal women

Chia Hui Wang, Min Huey Chung, Paul Chan, Jen Chen Tsai, Feng Chia Chen

Research output: Contribution to journalArticle

7 Citations (Scopus)


We conducted this study to investigate how an exercise program affects the risk components of metabolic syndrome (MS), serum interleukin (IL)-6 levels, and exercise capacity in postmenopausal women. A randomized clinical trial design was used. Women in an exercise group participated in a treadmill-exercise program for 12 weeks, whereas women in a control group maintained their customary lifestyle. Data on variables were collected at baseline and after 12 weeks of the study, which was completed by 46 women (mean age, 56.0 ± 7.0 y). Our results indicate endurance exercise exerted significant beneficial effects on waist circumference, serum high-density lipoprotein cholesterol (HDL-C) and IL-6 levels, and exercise capacity (all P <0.05). The beneficial effects on IL-6 and exercise capacity were correlated with improvements in HDL-C levels (r = -0.33, P = 0.03 and r = 0.31, P = 0.04, respectively). Our results suggest that health-care providers can incorporate an exercise program in treatments to improve the health of postmenopausal women.

Original languageEnglish
Pages (from-to)212-218
Number of pages7
JournalGeriatric Nursing
Issue number3
Publication statusPublished - 2014



  • Exercise capacity
  • Exercise training
  • Interleukin-6
  • Metabolic syndrome
  • Postmenopausal women

ASJC Scopus subject areas

  • Gerontology
  • Medicine(all)

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