Effects of elastic resistance exercise after total knee replacement on muscle mass and physical function in elderly women with osteoarthritis: A randomized controlled trial

Chun-De Liao, Jau-Yih Tsauo, Yen-Shuo Chiu, Jan-Wen Ku, Shih-Wei Huang, Tsan-Hon Liou

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Knee osteoarthritis (KOA) and age are associated with high sarcopenia risk, especially in patients who have received total knee replacement (TKR). The purpose of this study was to identify the effects of elastic resistance exercise training (RET) after TKR on muscle mass and physical outcomes in older women with KOA.Sixty older women who received unilateral primary TKR surgery were randomized to an experimental group (EG), which received 12 weeks of postoperative elastic RET, or a control group (CG), which received standard care. The outcome measures included physical function performance (i.e., Timed Up & Go [TUG], gait speed [GS], forward reach, single-leg stance, timed chair rise), appendicular lean mass (ALM), and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). The assessment time points were 2 weeks prior to surgery (T0), 1 month after surgery (T1; before RET), and 4 months after surgery (T2; upon completion of RET). RESULTS: After 12 weeks of postoperative elastic RET, the EG exhibited a significantly greater change in ALM (mean difference [MD], 0.81 kg; P = .004) than the CG. Elastic RET also exerted significant effects on TUG and GS with MDs of 0.28 m/s (P < .001) and -2.66 s (P < .001), respectively.A 12-week elastic RET program after TKR exerted benefits on muscle mass, mobility, and WOMAC functional outcomes in older women with KOA.

Original languageEnglish
JournalAmerican Journal of Physical Medicine and Rehabilitation
Publication statusE-pub ahead of print - Nov 4 2019


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