Effects of bilateral T2-sympathectomy on static and dynamic heart rate responses to exercise in hyperhidrosis patients

Hua Ting, Shin Da Lee, Ai Hui Chung, Ming Lung Chuang, Gin Den Chen, Jiuan Miaw Liao, Chen Lurng Chang, Thomas S M Chiou, Tzer Bin Lin

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2 Citations (Scopus)


The static/dynamic changes of gas exchange, heart rate (HR) and blood pressure in terms of work rate (WR) and WR changes in ramp exercise were investigated by cardio-pulmonary exercise tests (CPETs) in hyperhidrosis patients before (W0), one week (W1) and four weeks (W4) after bilateral T2-sympathectomy. Accompanied by constant oxygen consumption and WR at peak exercise and similar oxygen debt in recovery, the HR significantly (p <0.05) decreased statically in all stages of CPET, but was not altered dynamically, i.e., similar slope but significantly diminished intercept in HR changes versus WR changes (70 ± 6.0 vs. 82 ± 19 beats/min, p <0.01), in W1 (n = 11), compared to W0 (n = 13). However, this surgical effect on static HR changes seemed to have disappeared in W4 (n = 8), albeit at that time the static blood pressure decreased significantly during exercise. These findings suggest that bilateral T2-sympathectomy will reduce static HR without causing cardiovascular insufficiency in one week, and would then recover by one month in hyperhidrosis patients.

Original languageEnglish
Pages (from-to)74-80
Number of pages7
JournalAutonomic Neuroscience: Basic and Clinical
Issue number1-2
Publication statusPublished - Aug 31 2005
Externally publishedYes



  • Autonomic nervous system
  • Endoscopic transthoracic sympathectomy
  • Gas exchange
  • Hemodynamics
  • Sympathetic cardiac nerve

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems

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