Effects of 100-km ultramarathon on acute kidney injury

Wei Fong Kao, Sen Kuang Hou, Yu Hui Chiu, Shang Lin Chou, Fon Chu Kuo, Shih Hao Wang, Jin Jong Chen

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective: To evaluate the prevalence and characteristics of acute kidney injury (AKI) in 100-km ultramarathon runners. Design: Prospective observational study. Setting: The 2011 Soochow University ultramarathon, in which each athlete ran for 100 km. Participants: All Taiwanese entrants who participated in the 100-km race and lived in the northern part of Taiwan were invited to participate in the study. Main Outcome Measures: Acute kidney injury was defined using the Acute Kidney Injury Network criteria. Blood and urine samples were collected 1 week before, immediately after, and 1 day after the race. Results: Immediately after the race, 85% (22) of the 26 subjects were diagnosed with AKI, 65% (16) with moderate dehydration, 23% (6) with muscle cramps, and 12% (3) with hematuria. Body weight was significantly decreased from prerace to all postrace measurements. Plasma levels of potassium ion, creatinine, renin, and aldosterone were significantly elevated immediately after the race and then significantly reduced 1 day after the race. Changes in plasma levels of sodium, creatine kinase, and creatine kinase - MB, as well as urine potassium and creatinine, were indicative of AKI. Conclusions: Transient AKI and muscle cramps are very common in 100-km ultramarathon runners. All transient ultra-runners who developed AKI in this study recovered their renal function 1 day later. Clinical Relevance: Ultramarathon running is associated with a wide range of significant changes in hematological parameters, several of which can be associated with potentially serious renal and physiological abnormalities.

Original languageEnglish
Pages (from-to)49-54
Number of pages6
JournalClinical Journal of Sport Medicine
Volume25
Issue number1
DOIs
Publication statusPublished - Jan 13 2015

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Acute Kidney Injury
Muscle Cramp
Creatinine
Potassium
Urine
Kidney
MB Form Creatine Kinase
Hematuria
Creatine Kinase
Aldosterone
Taiwan
Dehydration
Renin
Athletes
Observational Studies
Sodium
Body Weight
Outcome Assessment (Health Care)
Prospective Studies
Ions

Keywords

  • acute kidney injury
  • AKI
  • renal function
  • ultramarathon

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Medicine(all)

Cite this

Kao, W. F., Hou, S. K., Chiu, Y. H., Chou, S. L., Kuo, F. C., Wang, S. H., & Chen, J. J. (2015). Effects of 100-km ultramarathon on acute kidney injury. Clinical Journal of Sport Medicine, 25(1), 49-54. https://doi.org/10.1097/JSM.0000000000000116

Effects of 100-km ultramarathon on acute kidney injury. / Kao, Wei Fong; Hou, Sen Kuang; Chiu, Yu Hui; Chou, Shang Lin; Kuo, Fon Chu; Wang, Shih Hao; Chen, Jin Jong.

In: Clinical Journal of Sport Medicine, Vol. 25, No. 1, 13.01.2015, p. 49-54.

Research output: Contribution to journalArticle

Kao, WF, Hou, SK, Chiu, YH, Chou, SL, Kuo, FC, Wang, SH & Chen, JJ 2015, 'Effects of 100-km ultramarathon on acute kidney injury', Clinical Journal of Sport Medicine, vol. 25, no. 1, pp. 49-54. https://doi.org/10.1097/JSM.0000000000000116
Kao, Wei Fong ; Hou, Sen Kuang ; Chiu, Yu Hui ; Chou, Shang Lin ; Kuo, Fon Chu ; Wang, Shih Hao ; Chen, Jin Jong. / Effects of 100-km ultramarathon on acute kidney injury. In: Clinical Journal of Sport Medicine. 2015 ; Vol. 25, No. 1. pp. 49-54.
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