Effect of O2-plasma treatment on surface characteristics and osteoblast-Like MG-63 cells response of Ti-30Nb-1Fe-1Hf alloy

En Yu Wu, Keng Liang Ou, Shih Fu Ou, Klaus D. Jandt, Yung Ning Pan

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7 Citations (Scopus)


In this study, the effect of O2-plasma treatment with various powers on the surface characteristics and also the cell response of the Ti-30Nb-1Fe-1Hf alloy were investigated. Surface characteristics of Ti-30Nb-1Fe-1Hf alloy were evaluated by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray powder diffractometer (XRPD) and wettability test. The results show that the surface roughness of the alloy decreases after O2-plasma treatment, and also with increased plasma power. By XPS analyses, both Ti valence states of Ti 2+, Ti3+ and Ti4+ as well as Nb valence states of Nb2+, Nb4+ and Nb5+ can be detected in the oxide films. Also, the concentrations of TiO2 and Nb 2O5 increase with increasing O2-plasma power. The results also show that the contact angle decreases as the alloy is modified by O2-plasma treatment, and therefore, the treated alloys can be expected to be more hydrophilic. On the other hand, for the evaluation of cell response, cell (MG-63) culture was performed. The results show that the oxidation effect on the alloy surface brought about by O2-plasma treatment enhances the spreading of cells. In addition, in vitro tests suggest that cell spreading on Ti-30Nb-1Fe-1Hf alloy is similar to that on Ti-6A1-4V alloy, whereas, cell adhesion on Ti-30Nb-1Fe-1Hf alloy is better than that on Ti-6A1-4V alloy.

Original languageEnglish
Pages (from-to)891-898
Number of pages8
JournalMaterials Transactions
Issue number4
Publication statusPublished - Apr 2009


  • Cell response
  • O-plasma
  • Oxidation
  • Ti-30Nb-1Fe-1Hf alloy

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering
  • Mechanics of Materials


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