Effect of electrostatic field on proliferation and cytokine secretion of macrophage cells

Yi Ching Ho, Shao Yi Hou, Tzan Fang, Hsuan Liang Liu, Hsu Wei Fang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Electricity has been shown to exhibit significant effects on immunological responses in many studies. In this study, an electrostatic filed induced device was first applied to the macrophage cell culturing process. Mouse macrophage-like cells J774 A.1 were exposed to the electrostatic field of 1.5 kV for 1, 2, and 6 days, respectively. The results show that the electrostatic field can inhibit cell proliferation and TNF-α secretion in six days. Cell proliferation is decreased and TNF-α secretion is increased with increasing voltage applied from 0 kV to 0.8 kV and 1.2 kV of the electrostatic fields.

Original languageEnglish
Pages (from-to)47-52
Number of pages6
JournalBiomedical Engineering - Applications, Basis and Communications
Volume20
Issue number1
DOIs
Publication statusPublished - Jan 1 2008
Externally publishedYes

Keywords

  • Cell proliferation
  • Cytokine
  • Electrostatic field
  • Macrophage

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomedical Engineering

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