Effect of electroacupuncture on blood pressure and adrenal nerve activity in anesthetized rats

Tzer B. Lin, Tsu Ching Fu

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The neural mechanism underlying the effect of electroacupuncture (Ea) on arterial blood pressure (BP) and adrenal nerve activity (ANA) was investigated in anesthetized rats. Tsusanli (St-36) and Hoku (Li-4) were tested with combinations of two different frequencies (3 and 30 Hz) with various stimulation intensities of Ea. At Tsusanli, no effect was found, while at Hoku, an elevation of BP in parallel with ANA was elicited during Ea when the intensity was 5xT or higher. The pattern of the pressor response caused by the low frequency Ea (LFEa, 3 Hz) was a tonic one, while a phasic one was induced by the high frequency Ea (HFEa, 30 Hz). When both Hoku were simultaneously stimulated with the same frequency, the latency to reach the maximal effect was shortened. However, when two different frequencies were used instead, a response characterized by a combination of both phasic and tonic effect was obtained. In bilateral Ea with idential frequency but different onset time, the pressor effect elicited by the latter Ea showed no further increase during the stimulation period, however, when different frequencies were employed, each Ea elicited its own effect independently. The pressor effect elicited by Ea was abolished by regitine but not affected by adrenalectomy. It is concluded that a LFEa and a HFEa at Hoku with appropriate stimulation parameters can increase BP which is mainly due to potentiation of the sympathetic vasoconstrictor tone but via different central mechanisms. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalNeuroscience Letters
Volume285
Issue number1
DOIs
Publication statusPublished - May 5 2000
Externally publishedYes

Fingerprint

Electroacupuncture
Blood Pressure
Phentolamine
Adrenalectomy
Vasoconstrictor Agents
Arterial Pressure

Keywords

  • Adrenal nerve
  • Blood pressure
  • Electroacupuncture
  • Frequency
  • Hoku
  • Rat
  • Tsusanli

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Effect of electroacupuncture on blood pressure and adrenal nerve activity in anesthetized rats. / Lin, Tzer B.; Fu, Tsu Ching.

In: Neuroscience Letters, Vol. 285, No. 1, 05.05.2000, p. 37-40.

Research output: Contribution to journalArticle

@article{66b328f966b54f1fb49a64374b626856,
title = "Effect of electroacupuncture on blood pressure and adrenal nerve activity in anesthetized rats",
abstract = "The neural mechanism underlying the effect of electroacupuncture (Ea) on arterial blood pressure (BP) and adrenal nerve activity (ANA) was investigated in anesthetized rats. Tsusanli (St-36) and Hoku (Li-4) were tested with combinations of two different frequencies (3 and 30 Hz) with various stimulation intensities of Ea. At Tsusanli, no effect was found, while at Hoku, an elevation of BP in parallel with ANA was elicited during Ea when the intensity was 5xT or higher. The pattern of the pressor response caused by the low frequency Ea (LFEa, 3 Hz) was a tonic one, while a phasic one was induced by the high frequency Ea (HFEa, 30 Hz). When both Hoku were simultaneously stimulated with the same frequency, the latency to reach the maximal effect was shortened. However, when two different frequencies were used instead, a response characterized by a combination of both phasic and tonic effect was obtained. In bilateral Ea with idential frequency but different onset time, the pressor effect elicited by the latter Ea showed no further increase during the stimulation period, however, when different frequencies were employed, each Ea elicited its own effect independently. The pressor effect elicited by Ea was abolished by regitine but not affected by adrenalectomy. It is concluded that a LFEa and a HFEa at Hoku with appropriate stimulation parameters can increase BP which is mainly due to potentiation of the sympathetic vasoconstrictor tone but via different central mechanisms. Copyright (C) 2000 Elsevier Science Ireland Ltd.",
keywords = "Adrenal nerve, Blood pressure, Electroacupuncture, Frequency, Hoku, Rat, Tsusanli",
author = "Lin, {Tzer B.} and Fu, {Tsu Ching}",
year = "2000",
month = "5",
day = "5",
doi = "10.1016/S0304-3940(00)01012-0",
language = "English",
volume = "285",
pages = "37--40",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Effect of electroacupuncture on blood pressure and adrenal nerve activity in anesthetized rats

AU - Lin, Tzer B.

AU - Fu, Tsu Ching

PY - 2000/5/5

Y1 - 2000/5/5

N2 - The neural mechanism underlying the effect of electroacupuncture (Ea) on arterial blood pressure (BP) and adrenal nerve activity (ANA) was investigated in anesthetized rats. Tsusanli (St-36) and Hoku (Li-4) were tested with combinations of two different frequencies (3 and 30 Hz) with various stimulation intensities of Ea. At Tsusanli, no effect was found, while at Hoku, an elevation of BP in parallel with ANA was elicited during Ea when the intensity was 5xT or higher. The pattern of the pressor response caused by the low frequency Ea (LFEa, 3 Hz) was a tonic one, while a phasic one was induced by the high frequency Ea (HFEa, 30 Hz). When both Hoku were simultaneously stimulated with the same frequency, the latency to reach the maximal effect was shortened. However, when two different frequencies were used instead, a response characterized by a combination of both phasic and tonic effect was obtained. In bilateral Ea with idential frequency but different onset time, the pressor effect elicited by the latter Ea showed no further increase during the stimulation period, however, when different frequencies were employed, each Ea elicited its own effect independently. The pressor effect elicited by Ea was abolished by regitine but not affected by adrenalectomy. It is concluded that a LFEa and a HFEa at Hoku with appropriate stimulation parameters can increase BP which is mainly due to potentiation of the sympathetic vasoconstrictor tone but via different central mechanisms. Copyright (C) 2000 Elsevier Science Ireland Ltd.

AB - The neural mechanism underlying the effect of electroacupuncture (Ea) on arterial blood pressure (BP) and adrenal nerve activity (ANA) was investigated in anesthetized rats. Tsusanli (St-36) and Hoku (Li-4) were tested with combinations of two different frequencies (3 and 30 Hz) with various stimulation intensities of Ea. At Tsusanli, no effect was found, while at Hoku, an elevation of BP in parallel with ANA was elicited during Ea when the intensity was 5xT or higher. The pattern of the pressor response caused by the low frequency Ea (LFEa, 3 Hz) was a tonic one, while a phasic one was induced by the high frequency Ea (HFEa, 30 Hz). When both Hoku were simultaneously stimulated with the same frequency, the latency to reach the maximal effect was shortened. However, when two different frequencies were used instead, a response characterized by a combination of both phasic and tonic effect was obtained. In bilateral Ea with idential frequency but different onset time, the pressor effect elicited by the latter Ea showed no further increase during the stimulation period, however, when different frequencies were employed, each Ea elicited its own effect independently. The pressor effect elicited by Ea was abolished by regitine but not affected by adrenalectomy. It is concluded that a LFEa and a HFEa at Hoku with appropriate stimulation parameters can increase BP which is mainly due to potentiation of the sympathetic vasoconstrictor tone but via different central mechanisms. Copyright (C) 2000 Elsevier Science Ireland Ltd.

KW - Adrenal nerve

KW - Blood pressure

KW - Electroacupuncture

KW - Frequency

KW - Hoku

KW - Rat

KW - Tsusanli

UR - http://www.scopus.com/inward/record.url?scp=0034607612&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034607612&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(00)01012-0

DO - 10.1016/S0304-3940(00)01012-0

M3 - Article

C2 - 10788702

AN - SCOPUS:0034607612

VL - 285

SP - 37

EP - 40

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 1

ER -