Abstract

PURPOSE:: In this study, the electrical discharge machining (EDM) was formed on the surface of the Ti-6Al-4V (Ti64) specimen. MATERIALS:: The properties of adhesion and proliferation of MG-63 cells were evaluated the interactions between the EDM-treated layer and cells. RESULTS:: The incorporation of oxygen roughened the EDM-treated specimen surface on a microscale, where the nanoscale pores were superimposed. The EDM-treated layer, which can generate the thick anatase TiO2 on the Ti64 surface, afforded a cytocompatible environment. In cell culture, alkaline phosphatase activity and osteocalcin can be dramatically enhanced on the EDM-treated surfaces when compared with the untreated surface. In addition, the increase in peak currents to the EDM functionalization led to enhancement of multiple osteoblast functions. CONCLUSIONS:: This study reveals that the chemistry and crystallinity of the EDM-treated layer played important roles in affecting osteoblastic responses to the specimens, which provided insight into the development of new biomedical implant surfaces.

Original languageEnglish
Pages (from-to)374-379
Number of pages6
JournalImplant Dentistry
Volume22
Issue number4
DOIs
Publication statusPublished - Aug 2013

Fingerprint

Osteocalcin
Osteoblasts
Alkaline Phosphatase
Cell Culture Techniques
Oxygen
titanium alloy (TiAl6V4)
titanium dioxide

Keywords

  • MG-63 cells
  • surface modification
  • x-ray photoelectron spectroscopy

ASJC Scopus subject areas

  • Oral Surgery

Cite this

Effect of electrical discharging on formation of nanoporous biocompatible layer on Ti-6Al-4V alloys. / Yang, Tzu Sen; Huang, Mao Suan; Wang, Mao Sheng; Lin, Ming Hong; Tsai, Meng Yuan; Wang Wang, Pei Yi.

In: Implant Dentistry, Vol. 22, No. 4, 08.2013, p. 374-379.

Research output: Contribution to journalArticle

Yang, Tzu Sen ; Huang, Mao Suan ; Wang, Mao Sheng ; Lin, Ming Hong ; Tsai, Meng Yuan ; Wang Wang, Pei Yi. / Effect of electrical discharging on formation of nanoporous biocompatible layer on Ti-6Al-4V alloys. In: Implant Dentistry. 2013 ; Vol. 22, No. 4. pp. 374-379.
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