Effect of carbon nanotubes on in vitro cellular responses for bioglass application

Jhih Ni Lin, Chih Yang Yeh, Yung Ning Pan, Ming Chin Lin, Fang Yu Fan

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Composite materials have been widely used in the field of biomedical science. In this study, the optimal concentration of bioglass/carbon nanotubes (BG/CNTs) in a composite powder was investigated. The composite was produced using the sol-gel process. When CNTs were added, they provided a crystal nucleation site for BG nanoparticles and decreased the heat treatment temperature required (from 700 °C to 500 °C). Compared to the BG group, a suitable quantity of CNTs increased the pore size (12.67 nm) of the composite materials. Meanwhile, the BG/0.05 CNT group showed weight gain results and revealed a faster apatite formation rate after 3 days than other composites. The apatite layer (which increased in thickness from 1.69 μm to 12.51 μm) was observed using scanning electron microscopy after 7 days. Additionally, the proliferation of the MG63 cell line showed an excellent performance with some BG/CNT ratios. It should be noted, however, that an excessive number (>0.05 wt%) of CNTs as filler in a BG matrix reduces cell growth.

Original languageEnglish
Pages (from-to)141-143
Number of pages3
JournalMaterials Letters
Publication statusPublished - Jan 15 2019


  • Apatite deposition
  • Bioglass
  • Carbon nanotubes
  • Sol-gel process

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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