TY - JOUR
T1 - Effect of air pollution on blood pressure, blood lipids, and blood sugar
T2 - A population-based approach
AU - Chuang, Kai Jen
AU - Yan, Yuan Horng
AU - Cheng, Tsun Jen
N1 - Funding Information:
This work was supported, in part, by National Science Council (NSC) grants 095-SAF-I-564-602-TMS and NSC 097-EPAM-002-001 .
PY - 2010/3
Y1 - 2010/3
N2 - Objective: To investigate changes in blood pressure, lipids, and sugar associated with changes in exposure to ambient air pollution. Methods: We conducted secondary analyses of blood pressure and biochemistry markers from Taiwanese Survey on Prevalence of Hyperglycemia, Hyperlipidemia, and Hypertension and air pollution monitoring data in 2002 by applying generalized additive models. Results: We observed increased particulate matter with aerodynamic diameters <10 μm was associated with elevated systolic blood pressure (an interquartile range, 34 μg/m, for 0.47 mmHg; 95% CI, -0.09 to 1.02), triglyceride, apolipoprotein B, hemoglobin A1c, and reduced high-density lipoprotein cholesterol. Elevated ozone was associated with increased diastolic blood pressure, apolipoprotein B, and hemoglobin A1c. Conclusions: Alterations of atherosclerotic indicators are associated with particulate matter with aerodynamic diameters <10 μm and ozone changes. This might provide a link between air pollution and progression of atherosclerotic cardiovascular diseases.
AB - Objective: To investigate changes in blood pressure, lipids, and sugar associated with changes in exposure to ambient air pollution. Methods: We conducted secondary analyses of blood pressure and biochemistry markers from Taiwanese Survey on Prevalence of Hyperglycemia, Hyperlipidemia, and Hypertension and air pollution monitoring data in 2002 by applying generalized additive models. Results: We observed increased particulate matter with aerodynamic diameters <10 μm was associated with elevated systolic blood pressure (an interquartile range, 34 μg/m, for 0.47 mmHg; 95% CI, -0.09 to 1.02), triglyceride, apolipoprotein B, hemoglobin A1c, and reduced high-density lipoprotein cholesterol. Elevated ozone was associated with increased diastolic blood pressure, apolipoprotein B, and hemoglobin A1c. Conclusions: Alterations of atherosclerotic indicators are associated with particulate matter with aerodynamic diameters <10 μm and ozone changes. This might provide a link between air pollution and progression of atherosclerotic cardiovascular diseases.
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U2 - 10.1097/JOM.0b013e3181ceff7a
DO - 10.1097/JOM.0b013e3181ceff7a
M3 - Article
C2 - 20190657
AN - SCOPUS:77949483486
SN - 1076-2752
VL - 52
SP - 258
EP - 262
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
IS - 3
ER -
