ED presentation of neutropenic enterocolitis in adult patients with acute leukemia

Teh F. Hsu, Hsien H. Huang, D. H T Yen, Wei Fong Kao, Jen D. Chen, Lee M. Wang, Chen Hsen Lee

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The purpose of this study was to investigate the initial clinical features and subsequent outcomes in patients with adult leukemia with typhlitis or neutropenic enterocolitis. A retrospective review of 10 episodes of neutropenic enterocolitis in nine patients (age range, 21-71 years) with acute leukemia from March 1, 1990, through February 28, 2002, was conducted. In clinical presentations, fever appears in all patients, followed by abdominal pain or tenderness (90%) and diarrhea (60%), respectively. In particular, three cases were coincidentally diagnosed as leukemia before any chemotherapy. The most common diagnostic modality used for the diagnosis of neutropenic enterocolitis was computed tomography (CT) scan (seven episodes). Medical treatments, including broad-spectrum antibiotics, bowel rest, and total parenteral nutrition, were applied to seven patients. Laparotomy with bowel resection was performed on two patients with bowel necrosis and severe peritonitis. Of all nine cases, six were fatal as a result of sepsis, a common complication of neutropenic enterocolitis. As the incidence of neutropenic enterocolitis increases in patients with acute leukemia, EPs should be alert and make an early diagnosis of this rapidly deteriorated and life-threatening disease.

Original languageEnglish
Pages (from-to)276-279
Number of pages4
JournalAmerican Journal of Emergency Medicine
Volume22
Issue number4
DOIs
Publication statusPublished - Jul 2004
Externally publishedYes

Fingerprint

Neutropenic Enterocolitis
Leukemia
Typhlitis
Total Parenteral Nutrition
Peritonitis
Laparotomy
Abdominal Pain
Early Diagnosis
Diarrhea
Sepsis
Fever
Necrosis
Tomography
Anti-Bacterial Agents
Drug Therapy
Incidence

Keywords

  • emergency department
  • leukemia
  • Typhlitis

ASJC Scopus subject areas

  • Emergency Medicine

Cite this

Hsu, T. F., Huang, H. H., Yen, D. H. T., Kao, W. F., Chen, J. D., Wang, L. M., & Lee, C. H. (2004). ED presentation of neutropenic enterocolitis in adult patients with acute leukemia. American Journal of Emergency Medicine, 22(4), 276-279. https://doi.org/10.1016/j.ajem.2004.02.014

ED presentation of neutropenic enterocolitis in adult patients with acute leukemia. / Hsu, Teh F.; Huang, Hsien H.; Yen, D. H T; Kao, Wei Fong; Chen, Jen D.; Wang, Lee M.; Lee, Chen Hsen.

In: American Journal of Emergency Medicine, Vol. 22, No. 4, 07.2004, p. 276-279.

Research output: Contribution to journalArticle

Hsu, TF, Huang, HH, Yen, DHT, Kao, WF, Chen, JD, Wang, LM & Lee, CH 2004, 'ED presentation of neutropenic enterocolitis in adult patients with acute leukemia', American Journal of Emergency Medicine, vol. 22, no. 4, pp. 276-279. https://doi.org/10.1016/j.ajem.2004.02.014
Hsu, Teh F. ; Huang, Hsien H. ; Yen, D. H T ; Kao, Wei Fong ; Chen, Jen D. ; Wang, Lee M. ; Lee, Chen Hsen. / ED presentation of neutropenic enterocolitis in adult patients with acute leukemia. In: American Journal of Emergency Medicine. 2004 ; Vol. 22, No. 4. pp. 276-279.
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