Early-life indoor environmental exposures increase the risk of childhood asthma

Yang Ching Chen, Ching Hui Tsai, Yungling Leo Lee

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We aim to explore the relationships between exposure to dampness, pets, and environmental tobacco smoke (ETS) early in life and asthma in Taiwanese children, and to discuss their links to early- and late-onset asthma. We conducted a 1:2 matched case-control study from the Taiwan Children Health Study, which was a nationwide study that recruited 12-to-14 year-old school children in 14 communities. The 579 mothers of the participants were interviewed by telephone about their children's environmental exposures before they were 5 years old, including the in-utero period. Childhood asthma was associated with exposure to early life environmental factors, such as cockroaches (OR = 2.16; 95% CI, 1.15-4.07), visible mould (OR = 1.75; 95% CI, 1.15-2.67), mildewy odors (OR = 5.04; 95% CI, 2.42-10.50), carpet (OR = 2.36; 95% CI, 1.38-4.05), pets (OR = 2.11; 95% CI, 1.20-3.72), and more than one hour of ETS per day (OR = 1.93; 95% CI, 1.16-3.23). The ORs for mildewy odors, feather pillows, and ETS during early childhood were greater among children with late-onset asthma. Cockroaches, carpet, pets, and in-utero exposures to ETS affected the timing of early-onset asthma. Exposure to these factors led to dose-responsiveness in the risk of asthma. And the earlier exposures may trigger the earlier onset. Interventions in avoiding these environmental exposures are necessary for early-prevention of childhood asthma.

Original languageEnglish
Pages (from-to)19-25
Number of pages7
JournalInternational Journal of Hygiene and Environmental Health
Volume215
Issue number1
DOIs
Publication statusPublished - Dec 1 2011
Externally publishedYes

Fingerprint

Environmental Exposure
Asthma
Smoke
Tobacco
Pets
Cockroaches
Feathers
Taiwan
Telephone
Case-Control Studies
Fungi
Mothers

Keywords

  • Asthma
  • Cockroach
  • Environmental tobacco smoke
  • Moulds
  • Pet

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Early-life indoor environmental exposures increase the risk of childhood asthma. / Chen, Yang Ching; Tsai, Ching Hui; Lee, Yungling Leo.

In: International Journal of Hygiene and Environmental Health, Vol. 215, No. 1, 01.12.2011, p. 19-25.

Research output: Contribution to journalArticle

@article{64a526dfbbff4788b8f8ccb5d719956c,
title = "Early-life indoor environmental exposures increase the risk of childhood asthma",
abstract = "We aim to explore the relationships between exposure to dampness, pets, and environmental tobacco smoke (ETS) early in life and asthma in Taiwanese children, and to discuss their links to early- and late-onset asthma. We conducted a 1:2 matched case-control study from the Taiwan Children Health Study, which was a nationwide study that recruited 12-to-14 year-old school children in 14 communities. The 579 mothers of the participants were interviewed by telephone about their children's environmental exposures before they were 5 years old, including the in-utero period. Childhood asthma was associated with exposure to early life environmental factors, such as cockroaches (OR = 2.16; 95{\%} CI, 1.15-4.07), visible mould (OR = 1.75; 95{\%} CI, 1.15-2.67), mildewy odors (OR = 5.04; 95{\%} CI, 2.42-10.50), carpet (OR = 2.36; 95{\%} CI, 1.38-4.05), pets (OR = 2.11; 95{\%} CI, 1.20-3.72), and more than one hour of ETS per day (OR = 1.93; 95{\%} CI, 1.16-3.23). The ORs for mildewy odors, feather pillows, and ETS during early childhood were greater among children with late-onset asthma. Cockroaches, carpet, pets, and in-utero exposures to ETS affected the timing of early-onset asthma. Exposure to these factors led to dose-responsiveness in the risk of asthma. And the earlier exposures may trigger the earlier onset. Interventions in avoiding these environmental exposures are necessary for early-prevention of childhood asthma.",
keywords = "Asthma, Cockroach, Environmental tobacco smoke, Moulds, Pet",
author = "Chen, {Yang Ching} and Tsai, {Ching Hui} and Lee, {Yungling Leo}",
year = "2011",
month = "12",
day = "1",
doi = "10.1016/j.ijheh.2011.07.004",
language = "English",
volume = "215",
pages = "19--25",
journal = "International Journal of Hygiene and Environmental Health",
issn = "1438-4639",
publisher = "Urban und Fischer Verlag Jena",
number = "1",

}

TY - JOUR

T1 - Early-life indoor environmental exposures increase the risk of childhood asthma

AU - Chen, Yang Ching

AU - Tsai, Ching Hui

AU - Lee, Yungling Leo

PY - 2011/12/1

Y1 - 2011/12/1

N2 - We aim to explore the relationships between exposure to dampness, pets, and environmental tobacco smoke (ETS) early in life and asthma in Taiwanese children, and to discuss their links to early- and late-onset asthma. We conducted a 1:2 matched case-control study from the Taiwan Children Health Study, which was a nationwide study that recruited 12-to-14 year-old school children in 14 communities. The 579 mothers of the participants were interviewed by telephone about their children's environmental exposures before they were 5 years old, including the in-utero period. Childhood asthma was associated with exposure to early life environmental factors, such as cockroaches (OR = 2.16; 95% CI, 1.15-4.07), visible mould (OR = 1.75; 95% CI, 1.15-2.67), mildewy odors (OR = 5.04; 95% CI, 2.42-10.50), carpet (OR = 2.36; 95% CI, 1.38-4.05), pets (OR = 2.11; 95% CI, 1.20-3.72), and more than one hour of ETS per day (OR = 1.93; 95% CI, 1.16-3.23). The ORs for mildewy odors, feather pillows, and ETS during early childhood were greater among children with late-onset asthma. Cockroaches, carpet, pets, and in-utero exposures to ETS affected the timing of early-onset asthma. Exposure to these factors led to dose-responsiveness in the risk of asthma. And the earlier exposures may trigger the earlier onset. Interventions in avoiding these environmental exposures are necessary for early-prevention of childhood asthma.

AB - We aim to explore the relationships between exposure to dampness, pets, and environmental tobacco smoke (ETS) early in life and asthma in Taiwanese children, and to discuss their links to early- and late-onset asthma. We conducted a 1:2 matched case-control study from the Taiwan Children Health Study, which was a nationwide study that recruited 12-to-14 year-old school children in 14 communities. The 579 mothers of the participants were interviewed by telephone about their children's environmental exposures before they were 5 years old, including the in-utero period. Childhood asthma was associated with exposure to early life environmental factors, such as cockroaches (OR = 2.16; 95% CI, 1.15-4.07), visible mould (OR = 1.75; 95% CI, 1.15-2.67), mildewy odors (OR = 5.04; 95% CI, 2.42-10.50), carpet (OR = 2.36; 95% CI, 1.38-4.05), pets (OR = 2.11; 95% CI, 1.20-3.72), and more than one hour of ETS per day (OR = 1.93; 95% CI, 1.16-3.23). The ORs for mildewy odors, feather pillows, and ETS during early childhood were greater among children with late-onset asthma. Cockroaches, carpet, pets, and in-utero exposures to ETS affected the timing of early-onset asthma. Exposure to these factors led to dose-responsiveness in the risk of asthma. And the earlier exposures may trigger the earlier onset. Interventions in avoiding these environmental exposures are necessary for early-prevention of childhood asthma.

KW - Asthma

KW - Cockroach

KW - Environmental tobacco smoke

KW - Moulds

KW - Pet

UR - http://www.scopus.com/inward/record.url?scp=82155173507&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82155173507&partnerID=8YFLogxK

U2 - 10.1016/j.ijheh.2011.07.004

DO - 10.1016/j.ijheh.2011.07.004

M3 - Article

VL - 215

SP - 19

EP - 25

JO - International Journal of Hygiene and Environmental Health

JF - International Journal of Hygiene and Environmental Health

SN - 1438-4639

IS - 1

ER -