Abstract
Background: Thousands of paraquat (PQ)-poisoned patients continue to die, particularly in developing countries. Although animal studies indicate that hemoperfusion (HP) within 2-4 h after intoxication effectively reduces mortality, the effect of early HP in humans remains unknown. Methods: We analyzed the records of all PQ-poisoned patients admitted to 2 hospitals between 2000 and 2009. Patients were grouped according to early or late HP and high-dose (oral cyclophosphamide [CP] and intravenous dexamethasone [DX]) or repeated pulse (intravenous methylprednisolone [MP] and CP, followed by DX and repeated MP and/or CP) PQ therapy. Early HP was defined as HP
| Original language | English |
|---|---|
| Article number | e48397 |
| Journal | PLoS One |
| Volume | 7 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Oct 29 2012 |
| Externally published | Yes |
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
Fingerprint Dive into the research topics of 'Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients'. Together they form a unique fingerprint.
Cite this
Hsu, C. W., Lin, J. L., Lin-Tan, D. T., Chen, K. H., Yen, T. H., Wu, M. S., & Lin, S. C. (2012). Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients. PLoS One, 7(10), [e48397]. https://doi.org/10.1371/journal.pone.0048397