Early diagnosis and treatment of lemierre syndrome in a neutropenic cancer patient

Ko Chiang Hsu, Shih Hung Tsai, Shi J. Chu, Chin Wang Hsu

Research output: Contribution to journalArticle

Abstract

Lemierre syndrome (LS) is a rare but potentially life-threatening disease. It originates from an oropharyngeal infection of the internal jugular vein (IJV) leading to thrombophlebitis and metastatic infection. We report a 42-year-old woman with gastric adenocarcinoma presenting with febrile neutropenia, sore throat, and a tender induration in the left neck. Early LS was diagnosed by finding thrombophlebitis of the IJV following oropharyngeal infection but without bacteremia. Antibiotic treatment led to freedom from metastatic infection. Physicians should suspect LS after identifying the "red-flag" signs, i.e., tender induration of the unilateral neck following an oropharyngeal infection. A prompt diagnosis can be made by finding thrombophlebitis of the IJV. Early antibiotic therapy may lead to favorable clinical outcomes.

Original languageEnglish
Pages (from-to)179-182
Number of pages4
JournalJournal of Medical Sciences (Taiwan)
Volume28
Issue number4
Publication statusPublished - Aug 2008
Externally publishedYes

Fingerprint

Lemierre Syndrome
Early Diagnosis
Thrombophlebitis
Jugular Veins
Infection
Neoplasms
Neck
Anti-Bacterial Agents
Therapeutics
Febrile Neutropenia
Pharyngitis
Bacteremia
Secondary Prevention
Stomach
Adenocarcinoma
Physicians

Keywords

  • Lemierre syndrome
  • Oropharyngeal infection
  • Thrombophlebitis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Early diagnosis and treatment of lemierre syndrome in a neutropenic cancer patient. / Hsu, Ko Chiang; Tsai, Shih Hung; Chu, Shi J.; Hsu, Chin Wang.

In: Journal of Medical Sciences (Taiwan), Vol. 28, No. 4, 08.2008, p. 179-182.

Research output: Contribution to journalArticle

Hsu, Ko Chiang ; Tsai, Shih Hung ; Chu, Shi J. ; Hsu, Chin Wang. / Early diagnosis and treatment of lemierre syndrome in a neutropenic cancer patient. In: Journal of Medical Sciences (Taiwan). 2008 ; Vol. 28, No. 4. pp. 179-182.
@article{c558cae279524e419284acdba9422c2c,
title = "Early diagnosis and treatment of lemierre syndrome in a neutropenic cancer patient",
abstract = "Lemierre syndrome (LS) is a rare but potentially life-threatening disease. It originates from an oropharyngeal infection of the internal jugular vein (IJV) leading to thrombophlebitis and metastatic infection. We report a 42-year-old woman with gastric adenocarcinoma presenting with febrile neutropenia, sore throat, and a tender induration in the left neck. Early LS was diagnosed by finding thrombophlebitis of the IJV following oropharyngeal infection but without bacteremia. Antibiotic treatment led to freedom from metastatic infection. Physicians should suspect LS after identifying the {"}red-flag{"} signs, i.e., tender induration of the unilateral neck following an oropharyngeal infection. A prompt diagnosis can be made by finding thrombophlebitis of the IJV. Early antibiotic therapy may lead to favorable clinical outcomes.",
keywords = "Lemierre syndrome, Oropharyngeal infection, Thrombophlebitis",
author = "Hsu, {Ko Chiang} and Tsai, {Shih Hung} and Chu, {Shi J.} and Hsu, {Chin Wang}",
year = "2008",
month = "8",
language = "English",
volume = "28",
pages = "179--182",
journal = "Journal of Medical Sciences",
issn = "1011-4564",
publisher = "國防醫學院",
number = "4",

}

TY - JOUR

T1 - Early diagnosis and treatment of lemierre syndrome in a neutropenic cancer patient

AU - Hsu, Ko Chiang

AU - Tsai, Shih Hung

AU - Chu, Shi J.

AU - Hsu, Chin Wang

PY - 2008/8

Y1 - 2008/8

N2 - Lemierre syndrome (LS) is a rare but potentially life-threatening disease. It originates from an oropharyngeal infection of the internal jugular vein (IJV) leading to thrombophlebitis and metastatic infection. We report a 42-year-old woman with gastric adenocarcinoma presenting with febrile neutropenia, sore throat, and a tender induration in the left neck. Early LS was diagnosed by finding thrombophlebitis of the IJV following oropharyngeal infection but without bacteremia. Antibiotic treatment led to freedom from metastatic infection. Physicians should suspect LS after identifying the "red-flag" signs, i.e., tender induration of the unilateral neck following an oropharyngeal infection. A prompt diagnosis can be made by finding thrombophlebitis of the IJV. Early antibiotic therapy may lead to favorable clinical outcomes.

AB - Lemierre syndrome (LS) is a rare but potentially life-threatening disease. It originates from an oropharyngeal infection of the internal jugular vein (IJV) leading to thrombophlebitis and metastatic infection. We report a 42-year-old woman with gastric adenocarcinoma presenting with febrile neutropenia, sore throat, and a tender induration in the left neck. Early LS was diagnosed by finding thrombophlebitis of the IJV following oropharyngeal infection but without bacteremia. Antibiotic treatment led to freedom from metastatic infection. Physicians should suspect LS after identifying the "red-flag" signs, i.e., tender induration of the unilateral neck following an oropharyngeal infection. A prompt diagnosis can be made by finding thrombophlebitis of the IJV. Early antibiotic therapy may lead to favorable clinical outcomes.

KW - Lemierre syndrome

KW - Oropharyngeal infection

KW - Thrombophlebitis

UR - http://www.scopus.com/inward/record.url?scp=52649132421&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52649132421&partnerID=8YFLogxK

M3 - Article

VL - 28

SP - 179

EP - 182

JO - Journal of Medical Sciences

JF - Journal of Medical Sciences

SN - 1011-4564

IS - 4

ER -