Early colonic carcinoma with extensive lymph node metastases: Case report and review of literature

Gi Shih Lien, Chun Nan Chen, Yeong-Shan Cheng, Sheng-Hsuan Chen, Shiann Pan, Mao-Chih Hsieh, Chia Lang Fang, Steven Itzkowitz

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

An 81-year-old woman had an early carcinoma invading focally into the upper submucosa of the middle-transverse colon, which was accompanied by extensive lymph node metastases and resulted in a poor prognosis. Although her tumor was small and flat, a rim of pale yellow-speckled mucosa adjacent to the tumor enabled its earlier detection. To further study the exceptional lymph node metastases we studied the expression of intestinal trefoil factor and sialyl Tn antigen immunohistochemically on the resected specimen. Their simultaneous expression in lymph node metastasis further supports the aggressive nature of this tumor.

Original languageEnglish
Pages (from-to)262-266
Number of pages5
JournalInternational Journal of Colorectal Disease
Volume16
Issue number4
DOIs
Publication statusPublished - 2001

Keywords

  • Colon
  • Early carcinoma
  • Intestinal trefoil factor
  • Metastases
  • Sialyl Tn

ASJC Scopus subject areas

  • Gastroenterology

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