DNA topoisomerases: Essential enzymes and lethal targets

A. Y. Chen, Leroy-Fong Liu

Research output: Contribution to journalArticle

746 Citations (Scopus)
Original languageEnglish
Pages (from-to)191-218
Number of pages28
JournalAnnual Review of Pharmacology and Toxicology
Volume34
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

DNA Topoisomerases
Intercalating Agents
Type II DNA Topoisomerase
Type I DNA Topoisomerase
Drug Resistance
DNA Damage
Animals
Enzymes

Keywords

  • anticancer drug
  • DNA damage
  • drug resistance
  • groove binder
  • intercalator

ASJC Scopus subject areas

  • Pharmacology
  • Toxicology

Cite this

DNA topoisomerases : Essential enzymes and lethal targets. / Chen, A. Y.; Liu, Leroy-Fong.

In: Annual Review of Pharmacology and Toxicology, Vol. 34, 1994, p. 191-218.

Research output: Contribution to journalArticle

@article{c9a79c92ebbf496f8a8aa62f610510c7,
title = "DNA topoisomerases: Essential enzymes and lethal targets",
keywords = "anticancer drug, DNA damage, drug resistance, groove binder, intercalator",
author = "Chen, {A. Y.} and Leroy-Fong Liu",
year = "1994",
language = "English",
volume = "34",
pages = "191--218",
journal = "Annual Review of Pharmacology and Toxicology",
issn = "0362-1642",
publisher = "Annual Reviews Inc.",

}

TY - JOUR

T1 - DNA topoisomerases

T2 - Essential enzymes and lethal targets

AU - Chen, A. Y.

AU - Liu, Leroy-Fong

PY - 1994

Y1 - 1994

KW - anticancer drug

KW - DNA damage

KW - drug resistance

KW - groove binder

KW - intercalator

UR - http://www.scopus.com/inward/record.url?scp=0028174984&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028174984&partnerID=8YFLogxK

M3 - Article

C2 - 8042851

AN - SCOPUS:0028174984

VL - 34

SP - 191

EP - 218

JO - Annual Review of Pharmacology and Toxicology

JF - Annual Review of Pharmacology and Toxicology

SN - 0362-1642

ER -