@article{edf3651d953d47649d9d5c406e903d4f,
title = "DNA polymerase I is not required for replication of linear chromosomes in Streptomyces",
abstract = "Both pol4 (encoding DNA polymerase I; Pol I) and a paralog were deleted from Streptomyces strains. Despite the UV sensitivity and slow growth caused by the ΔpolA mutation, the double mutant was viable. Thus, in contrast to a previous postulate, Pol I and its paralog are not essential for replication of Streptomyces chromosomes. Copyright {\textcopyright} 2008, American Society for Microbiology. All Rights Reserved.",
keywords = "bacterial DNA, DNA directed DNA polymerase beta, article, bacterial chromosome, biosynthesis, gene deletion, gene expression regulation, genetics, growth, development and aging, metabolism, microbial viability, radiation exposure, Streptomyces, ultraviolet radiation, bacterial growth, bacterial strain, bacterium mutant, chromosome replication, gene mutation, nonhuman, priority journal, radiosensitivity, Chromosomes, Bacterial, DNA Polymerase I, DNA, Bacterial, Gene Deletion, Microbial Viability, Mutagenesis, Insertional, Ultraviolet Rays",
author = "Tzu-Wen Huang and Hsiu-Hwei Chen",
note = "被引用次數：8 Export Date: 12 April 2016 CODEN: JOBAA 通訊地址: Chen, C. W.; Department of Life Sciences, Institute of Genome Sciences, National Yang-Ming University, Shih-Pai, Taipei 112, Taiwan; 電子郵件： cwchen@ym.edu.tw 化學物質/CAS: DNA Polymerase I, EC 2.7.7.-; DNA, Bacterial 參考文獻: Bao, K., Cohen, S.N., Recruitment of terminal protein to the ends of Streptomyces linear plasmids and chromosomes by a novel telomere-binding protein essential for linear DNA replication (2003) Genes Dev, 17, pp. 774-785; Bao, K., Cohen, S.N., Reverse transcriptase activity innate to DNA polymerase I and DNA topoisomerase I proteins of Streptomyces telomere complex (2004) Proc. Natl. Acad. Sci. USA, 101, pp. 14361-14366; Bao, K., Cohen, S.N., Terminal proteins essential for the replication of linear plasmids and chromosomes in Streptomyces (2001) Genes Dev, 15, pp. 1518-1527; Bentley, S. D., K. F. Chater, A.-M. Cerde{\~n}o-T{\'a}rraga, G. L. Challis, N. R. Thomson, K. D. James, D. E. Harris, M. A. Quail, H. Kieser, D. Harper, A. Bateman, S. Brown, G. Chandra, C. W. Chen, M. Collins, A. Cronin, A. Fraser, A. Goble, J. Hidalgo, T. Hornsby, S. Howarth, C. H. Huang, T. Kieser, L. Larke, L. Murphy, K. Oliver, S. O'Neil, E. Rabbinowitsch, M. A. Rajandream, K. Rutherford, S. Rutter, K. Seeger, D. Saunders, S. Sharp, R. Squares, S. Squares, K. Taylor, T. Warren, A. Wietzorrek, J. Woodward, B. G. Barrell, J. Parkhill, and D. A. Hopwood. 2002. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141-147Chang, P.C., Cohen, S.N., Bidirectional replication from an internal origin in a linear Streptomyces plasmid (1994) Science, 265, pp. 952-954; Chen, C.W., Complications and implications of linear bacterial chromosomes (1996) Trends Genet, 12, pp. 192-196; Gust, B., Challis, G.L., Fowler, K., Kieser, T., Chater, K.F., PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin (2003) Proc. Natl. Acad. Sci. USA, 100, pp. 1541-1546; Hopwood, D.A., Kieser, T., Wright, H.M., Bibb, M.J., Plasmids, recombination, and chromosomal mapping in Streptomyces lividans 66 (1983) J. Gen. Microbiol, 129, pp. 2257-2269; Huang, T.W., Chen, C.W., A recA null mutation may be generated in Streptomyces coelicolor (2006) J. Bacteriol, 188, pp. 6771-6779; Ikeda, H., Ishikawa, J., Hanamoto, A., Shinose, M., Kikuchi, H., Shiba, T., Sakaki, Y., Omura, S., Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis (2003) Nat Biotechnol, 21, pp. 526-531; Joyce, C.M., Grindley, N.D., Method for determining whether a gene of Escherichia coli is essential: Application to the polA gene (1984) J. Bacteriol, 158, pp. 636-643; Kieser, T., Bibb, M., Buttner, M.J., Chater, K.F., Hopwood, D.A., (2000) Practical Streptomyces genetics, , The John Innes Foundation, Norwich, United Kingdom; Laity, C., Chater, K.F., Lewis, C.G., Buttner, M.J., Genetic analysis of the φC31-specific phage growth limitation (Pgl) system of Streptomyces coelicolor A3(2) (1993) Mol. Microbiol, 7, pp. 329-336; Lee, L.-F., Chen, Y.-J., Kirby, R., Chen, C., Chen, C.W., A multidrug efflux system is involved in colony growth in Streptomyces lividans (2007) Microbiology, 153, pp. 924-934; Okazaki, R., Arisawa, M., Sugino, A., Slow joining of newly replicated DNA chains in DNA polymerase I-deficient Escherichia coli mutants (1971) Proc. Natl. Acad. Sci. USA, 68, pp. 2954-2957; Olivera, B.M., Bonhoeffer, F., Replication of Escherichia coli requires DNA polymerase I (1974) Nature, 250, pp. 513-514; Paget, M.S.B., Chamberlin, L., Atrih, A.M., Foster, S.J., Buttner, M.J., Evidence that the extracytoplasmic function sigma factor σ E is required for normal cell wall structure in Streptomyces coelicolor A3(2) (1999) J. Bacteriol, 181, pp. 204-211; Redenbach, M., Kieser, H.M., Denapaite, D., Eichner, A., Cullum, J., Kinashi, H., Hopwood, D.A., A set of ordered cosmids and a detailed genetic and physical map for the 8 Mb Streptomyces coelicolor A3(2) chromosome (1996) Mol. Microbiol, 21, pp. 77-96; Weaver, D., Karoonuthaisiri, N., Tsai, H.H., Huang, C.H., Ho, M.L., Gai, S., Patel, K.G., Kao, C.M., Genome plasticity in Streptomyces: Identification of 1 Mb TIRs in the S. coelicolor A3(2) chromosome (2004) Mol. Microbiol, 51, pp. 1535-1550; Yang, C.-C., Huang, C.-H., Li, C.-Y., Tsay, Y.-G., Lee, S.-C., Chen, C.W., The terminal proteins of linear Streptomyces chromosomes and plasmids: A novel class of replication priming proteins (2002) Mol. Microbiol, 43, pp. 297-305; Yang, C.-C., Chen, Y.-H., Tsai, H.-H., Huang, C.-H., Huang, T.-W., Chen, C.W., In vitro deoxynucleotidylation of the terminal protein of Streptomyces linear chromosomes (2006) Appl. Environ. Microbiol, 72, pp. 7959-7961",
year = "2008",
doi = "10.1128/JB.01335-07",
language = "English",
volume = "190",
pages = "755--758",
journal = "Journal of Bacteriology",
issn = "0021-9193",
publisher = "American Society for Microbiology",
number = "2",
}