Distal embolization versus combined embolization techniques for blunt splenic injuries

Comparison of the efficacy and complications

Yon Cheong Wong, Cheng Hsien Wu, Li Jen Wang, Huan Wu Chen, Kuo Ching Yuan, Being Chuan Lin, Yu Pao Hsu, Shih Ching Kang

Research output: Contribution to journalArticle

Abstract

Comparable failure rates of distal or proximal transcatheter arterial embolization (TAE) techniques for blunt splenic injuries have been reported. This study is to investigate the efficacy and complication of combining both TAE techniques. We included 26 patients of blunt splenic injuries for TAE therapy and randomized them into distal TAE and combined TAE groups. A prospective study was performed to compare their demographics, clinical parameters, hemograms, post-TAE splenic infarct volumes, splenic abscess and pancreatitis between the two groups. Of 26 patients, 17 received distal TAE, 9 received combined TAE. Their basic demographics, clinical parameters and hemograms did not differ. Mean systolic blood pressure of all patients was significantly elevated after TAE at 24 hours later. Three patients of distal TAE group had residual pseudoaneurysms in follow up. They were considered failures in distal TAE group as opposed to all successes in combined TAE group. The risk difference of failure of distal TAE was 17.6%. None developed post-TAE splenic abscess, massive splenic infarct or pancreatitis. The mean splenic infarct volume of distal TAE (10.9%) versus combined TAE groups (6.6%) was not significant (p = 0.481). Combined TAE is effective and safe to decrease the failure rates of non-operative management for blunt splenic injuries.

Original languageEnglish
Pages (from-to)95596-95605
Number of pages10
JournalOncotarget
Volume8
Issue number56
DOIs
Publication statusPublished - Jan 1 2017
Externally publishedYes

Fingerprint

Nonpenetrating Wounds
Splenic Infarction
Pancreatitis
Abscess
Demography
Blood Pressure
False Aneurysm
Prospective Studies
Therapeutics

Keywords

  • Efficacy
  • Embolization technique
  • Spleen infarct
  • Splenic abscess
  • Splenic injuries

ASJC Scopus subject areas

  • Oncology

Cite this

Distal embolization versus combined embolization techniques for blunt splenic injuries : Comparison of the efficacy and complications. / Wong, Yon Cheong; Wu, Cheng Hsien; Wang, Li Jen; Chen, Huan Wu; Yuan, Kuo Ching; Lin, Being Chuan; Hsu, Yu Pao; Kang, Shih Ching.

In: Oncotarget, Vol. 8, No. 56, 01.01.2017, p. 95596-95605.

Research output: Contribution to journalArticle

Wong, Yon Cheong ; Wu, Cheng Hsien ; Wang, Li Jen ; Chen, Huan Wu ; Yuan, Kuo Ching ; Lin, Being Chuan ; Hsu, Yu Pao ; Kang, Shih Ching. / Distal embolization versus combined embolization techniques for blunt splenic injuries : Comparison of the efficacy and complications. In: Oncotarget. 2017 ; Vol. 8, No. 56. pp. 95596-95605.
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