Disseminated intravascular coagulation in a stage IV colon cancer patient: Report of a case and review of the literature

Li Jen Kuo, Shuh Yan Leu, Mei Ching Liu, Chung Ming Chen

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Approximately 20% of patients with colorectal carcinoma are iniatally seen with stage IV of the disease. Here, we report a 45-year old female patient with synchronous sigmoid colon cancer and multiple liver metastases. She underwent a palliative anterior resection and hepatic arterial infusion pump implantation. Left lower leg swelling developed four days after the operation and then shortness of breath was noted. Emergency lower extremity duplex ultrasound study proved the presence of left deep venous thrombosis. Chest helical computed tomography showed bilateral pulmonary arterial thromboembolism. Laboratory tests revealed a rapid decline in platelet counts and fibrinogen level, and the presence of fibrin-degradation products in plasma. Under the impression of disseminated intravascular coagulation, systemic heparinization with low-molecular-weight herapin was employed. Clinically speaking, the patient improved gradually with rise of platelet counts to the normal range several days later.

Original languageEnglish
Pages (from-to)188-192
Number of pages5
JournalFormosan Journal of Surgery
Volume36
Issue number4
Publication statusPublished - 2003
Externally publishedYes

Fingerprint

Disseminated Intravascular Coagulation
Colonic Neoplasms
Platelet Count
Sigmoid Neoplasms
Fibrin Fibrinogen Degradation Products
Infusion Pumps
Spiral Computed Tomography
Liver Neoplasms
Pulmonary Embolism
Venous Thrombosis
Dyspnea
Fibrinogen
Colorectal Neoplasms
Lower Extremity
Leg
Reference Values
Emergencies
Thorax
Molecular Weight
Neoplasm Metastasis

Keywords

  • Colorectal cancer
  • Deep vein thrombosis
  • Disseminated intravascular coagulation

ASJC Scopus subject areas

  • Surgery

Cite this

Disseminated intravascular coagulation in a stage IV colon cancer patient : Report of a case and review of the literature. / Kuo, Li Jen; Leu, Shuh Yan; Liu, Mei Ching; Chen, Chung Ming.

In: Formosan Journal of Surgery, Vol. 36, No. 4, 2003, p. 188-192.

Research output: Contribution to journalArticle

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