Abstract
Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P
| Original language | English |
|---|---|
| Pages (from-to) | 121-127 |
| Number of pages | 7 |
| Journal | Clinical Imaging |
| Volume | 32 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 2008 |
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Keywords
- Fascicular sign
- Magnetic resonance (MR) imaging
- Peripheral nerve sheath tumor
- Split fat sign
- Target sign
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging. / Li, Chao Shiang; Huang, Guo Shu; Wu, Hong Da; Chen, Wei Tsung; Shih, Li Sun; Lii, Jiunn Ming; Duh, Shyi Jye; Chen, Ran Chou; Tu, Hsing Yang; Chan, Wing P.
In: Clinical Imaging, Vol. 32, No. 2, 03.2008, p. 121-127.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging
AU - Li, Chao Shiang
AU - Huang, Guo Shu
AU - Wu, Hong Da
AU - Chen, Wei Tsung
AU - Shih, Li Sun
AU - Lii, Jiunn Ming
AU - Duh, Shyi Jye
AU - Chen, Ran Chou
AU - Tu, Hsing Yang
AU - Chan, Wing P.
PY - 2008/3
Y1 - 2008/3
N2 - Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P
AB - Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P
KW - Fascicular sign
KW - Magnetic resonance (MR) imaging
KW - Peripheral nerve sheath tumor
KW - Split fat sign
KW - Target sign
UR - http://www.scopus.com/inward/record.url?scp=39649114561&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=39649114561&partnerID=8YFLogxK
U2 - 10.1016/j.clinimag.2007.05.006
DO - 10.1016/j.clinimag.2007.05.006
M3 - Article
C2 - 18313576
AN - SCOPUS:39649114561
VL - 32
SP - 121
EP - 127
JO - Clinical Imaging
JF - Clinical Imaging
SN - 0899-7071
IS - 2
ER -