Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

Chao Shiang Li; Guo Shu Huang; Hong Da Wu; Wei Tsung Chen; Li Sun Shih; Jiunn Ming Lii; Shyi Jye Duh; Ran Chou Chen; Hsing Yang Tu; Wing P. Chan

doi:10.1016/j.clinimag.2007.05.006

Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

Chao Shiang Li, Guo Shu Huang, Hong Da Wu, Wei Tsung Chen, Li Sun Shih, Jiunn Ming Lii, Shyi Jye Duh, Ran Chou Chen, Hsing Yang Tu, Wing P. Chan

Research output: Contribution to journal › Article › peer-review

103 Citations (Scopus)

Abstract

Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T₂-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P

Original language	English
Pages (from-to)	121-127
Number of pages	7
Journal	Clinical Imaging
Volume	32
Issue number	2
DOIs	https://doi.org/10.1016/j.clinimag.2007.05.006
Publication status	Published - Mar 2008

Keywords

Fascicular sign
Magnetic resonance (MR) imaging
Peripheral nerve sheath tumor
Split fat sign
Target sign

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.clinimag.2007.05.006

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title = "Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging",

abstract = "Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P",

keywords = "Fascicular sign, Magnetic resonance (MR) imaging, Peripheral nerve sheath tumor, Split fat sign, Target sign",

author = "Li, {Chao Shiang} and Huang, {Guo Shu} and Wu, {Hong Da} and Chen, {Wei Tsung} and Shih, {Li Sun} and Lii, {Jiunn Ming} and Duh, {Shyi Jye} and Chen, {Ran Chou} and Tu, {Hsing Yang} and Chan, {Wing P.}",

year = "2008",

month = mar,

doi = "10.1016/j.clinimag.2007.05.006",

language = "English",

volume = "32",

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T1 - Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

AU - Li, Chao Shiang

AU - Huang, Guo Shu

AU - Wu, Hong Da

AU - Chen, Wei Tsung

AU - Shih, Li Sun

AU - Lii, Jiunn Ming

AU - Duh, Shyi Jye

AU - Chen, Ran Chou

AU - Tu, Hsing Yang

AU - Chan, Wing P.

PY - 2008/3

Y1 - 2008/3

N2 - Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P

AB - Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P

KW - Fascicular sign

KW - Magnetic resonance (MR) imaging

KW - Peripheral nerve sheath tumor

KW - Split fat sign

KW - Target sign

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Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

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Keywords

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