Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging

Chao Shiang Li, Guo Shu Huang, Hong Da Wu, Wei Tsung Chen, Li Sun Shih, Jiunn Ming Lii, Shyi Jye Duh, Ran Chou Chen, Hsing Yang Tu, Wing P. Chan

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Abstract

Purpose: The objective of this study was to differentiate the magnetic resonance (MR) imaging appearance of benign peripheral nerve sheath tumors (PNSTs) from that of malignant PNSTs. Materials and methods: Twenty-six patients who underwent MR imaging and had a histologic diagnosis of benign (schwannoma, n=16; neurofibroma, n=1) or malignant (n=9) PNST were retrospectively reviewed. The size, location, shape, margin, and signal intensities of the tumors on precontrast and gadolinium-enhanced MR imaging were analyzed. In each patient, the presence or absence of split fat, target, and fascicular signs was determined. Results: The mean size of the benign PNSTs (3.4 cm, S.D.=2.5 cm) was significantly smaller than that of the malignant tumors (8.2 cm, S.D.=3.1 cm) (P1-weighted, T2-weighted, and contrast-enhanced MR images. The split fat and target signs were present more frequently in the benign PNSTs than in the malignant PNSTs (P

Original languageEnglish
Pages (from-to)121-127
Number of pages7
JournalClinical Imaging
Volume32
Issue number2
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Fascicular sign
  • Magnetic resonance (MR) imaging
  • Peripheral nerve sheath tumor
  • Split fat sign
  • Target sign

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Li, C. S., Huang, G. S., Wu, H. D., Chen, W. T., Shih, L. S., Lii, J. M., Duh, S. J., Chen, R. C., Tu, H. Y., & Chan, W. P. (2008). Differentiation of soft tissue benign and malignant peripheral nerve sheath tumors with magnetic resonance imaging. Clinical Imaging, 32(2), 121-127. https://doi.org/10.1016/j.clinimag.2007.05.006