Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET

Wu Huei Hsu, Nan Yung Hsu, Yeh Y. Shen, Ruoh Fang Yen, Chia Hung Kao

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas.

Original languageEnglish
Pages (from-to)47-52
Number of pages6
JournalCancer Investigation
Volume21
Issue number1
DOIs
Publication statusPublished - 2003
Externally publishedYes

Keywords

  • 18F-fluoro-2-deoxyglucose
  • Positron emission tomography
  • Solitary pulmonary metastases

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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