Differential parametric modulation of self-relatedness and emotions in different brain regions

Georg Northoff, Felix Schneider, Michael Rotte, Christian Matthiae, Claus Tempelmann, Christina Wiebking, Felix Bermpohl, Alexander Heinzel, Peter Danos, Hans Jochen Heinze, Bernhard Bogerts, Martin Walter, Jaak Panksepp

Research output: Contribution to journalArticle

88 Citations (Scopus)

Abstract

Our sense of self is strongly colored by emotions although at the same time we are well able to distinguish affect and self. Using functional magnetic resonance imaging, we here tested for the differential effects of self-relatedness and emotion dimensions (valence, intensity) on parametric modulation of neural activity during perception of emotional stimuli. We observed opposite parametric modulation of self-relatedness and emotion dimensions in the dorsomedial prefrontal cortex and the ventral striatum/ nucleus accumbens, whereas neural activity in subcortical regions (tectum, right amygdala, hypothalamus) was modulated by self-relatedness and emotion dimensions in the same direction. In sum, our results demonstrate that self-relatedness is closely linked to emotion dimensions of valence and intensity in many lower subcortical brain regions involved in basic emotional systems and, at the same time, distinct from them in higher cortical regions that mediate cognitive processes necessary for becoming aware of one's self, for example self -consciousness.

Original languageEnglish
Pages (from-to)369-382
Number of pages14
JournalHuman Brain Mapping
Volume30
Issue number2
DOIs
Publication statusPublished - Feb 2009

Fingerprint

Emotions
Brain
Nucleus Accumbens
Amygdala
Prefrontal Cortex
Consciousness
Hypothalamus
Magnetic Resonance Imaging

Keywords

  • Affect
  • Functional imaging
  • Prefrontal cortex
  • Self

ASJC Scopus subject areas

  • Clinical Neurology
  • Anatomy
  • Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Northoff, G., Schneider, F., Rotte, M., Matthiae, C., Tempelmann, C., Wiebking, C., ... Panksepp, J. (2009). Differential parametric modulation of self-relatedness and emotions in different brain regions. Human Brain Mapping, 30(2), 369-382. https://doi.org/10.1002/hbm.20510

Differential parametric modulation of self-relatedness and emotions in different brain regions. / Northoff, Georg; Schneider, Felix; Rotte, Michael; Matthiae, Christian; Tempelmann, Claus; Wiebking, Christina; Bermpohl, Felix; Heinzel, Alexander; Danos, Peter; Heinze, Hans Jochen; Bogerts, Bernhard; Walter, Martin; Panksepp, Jaak.

In: Human Brain Mapping, Vol. 30, No. 2, 02.2009, p. 369-382.

Research output: Contribution to journalArticle

Northoff, G, Schneider, F, Rotte, M, Matthiae, C, Tempelmann, C, Wiebking, C, Bermpohl, F, Heinzel, A, Danos, P, Heinze, HJ, Bogerts, B, Walter, M & Panksepp, J 2009, 'Differential parametric modulation of self-relatedness and emotions in different brain regions', Human Brain Mapping, vol. 30, no. 2, pp. 369-382. https://doi.org/10.1002/hbm.20510
Northoff, Georg ; Schneider, Felix ; Rotte, Michael ; Matthiae, Christian ; Tempelmann, Claus ; Wiebking, Christina ; Bermpohl, Felix ; Heinzel, Alexander ; Danos, Peter ; Heinze, Hans Jochen ; Bogerts, Bernhard ; Walter, Martin ; Panksepp, Jaak. / Differential parametric modulation of self-relatedness and emotions in different brain regions. In: Human Brain Mapping. 2009 ; Vol. 30, No. 2. pp. 369-382.
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