Differential effect of high dietary fat intakes on haemorheological parameters in rats

Cheng Jeng Tai, Chao Hsiang Chen, Hui Hsin Chen, Hong Jen Liang

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

High dietary intake of fats has been thought to be one of the major risk factors for the development of CVD. Less is known about the possible influence of fats from various sources on haemorheological abnormalities, which are considered an important factor in the pathogenesis of these diseases. The goal of the present study was to investigate effects of high-fat diets enriched in unsaturated fatty acids (USFA), SFA or trans-fatty acids (TFA), respectively, on haemorheological parameters in rats. Wistar female rats were divided into four groups and fed diets based on the AIN-93M formulation containing approximately 10% energy from soyabean oil (control group) or 40% energy from soyabean oil (USFA), palm oil (SFA) and vegetable shortening (TFA) for 8 weeks. The results showed that rats fed high-fat diets exhibited significant increases in serum TAG levels (P

Original languageEnglish
Pages (from-to)977-983
Number of pages7
JournalBritish Journal of Nutrition
Volume103
Issue number7
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Trans Fatty Acids
Dietary Fats
High Fat Diet
Unsaturated Fatty Acids
Oils
Vegetables
Wistar Rats
Fats
Diet
Control Groups
Serum
palm oil

Keywords

  • Blood viscosity
  • Erythrocyte aggregation
  • Erythrocyte deformability
  • Free radicals
  • High fat intake
  • Plasma viscosity
  • SFA
  • Trans-fatty acids
  • Unsaturated fatty acids

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Medicine(all)

Cite this

Differential effect of high dietary fat intakes on haemorheological parameters in rats. / Tai, Cheng Jeng; Chen, Chao Hsiang; Chen, Hui Hsin; Liang, Hong Jen.

In: British Journal of Nutrition, Vol. 103, No. 7, 04.2010, p. 977-983.

Research output: Contribution to journalArticle

Tai, Cheng Jeng ; Chen, Chao Hsiang ; Chen, Hui Hsin ; Liang, Hong Jen. / Differential effect of high dietary fat intakes on haemorheological parameters in rats. In: British Journal of Nutrition. 2010 ; Vol. 103, No. 7. pp. 977-983.
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