Abstract
High dietary intake of fats has been thought to be one of the major risk factors for the development of CVD. Less is known about the possible influence of fats from various sources on haemorheological abnormalities, which are considered an important factor in the pathogenesis of these diseases. The goal of the present study was to investigate effects of high-fat diets enriched in unsaturated fatty acids (USFA), SFA or trans-fatty acids (TFA), respectively, on haemorheological parameters in rats. Wistar female rats were divided into four groups and fed diets based on the AIN-93M formulation containing approximately 10% energy from soyabean oil (control group) or 40% energy from soyabean oil (USFA), palm oil (SFA) and vegetable shortening (TFA) for 8 weeks. The results showed that rats fed high-fat diets exhibited significant increases in serum TAG levels (P
| Original language | English |
|---|---|
| Pages (from-to) | 977-983 |
| Number of pages | 7 |
| Journal | British Journal of Nutrition |
| Volume | 103 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Apr 2010 |
Keywords
- Blood viscosity
- Erythrocyte aggregation
- Erythrocyte deformability
- Free radicals
- High fat intake
- Plasma viscosity
- SFA
- Trans-fatty acids
- Unsaturated fatty acids
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Medicine(all)