Abstract
High dietary intake of fats has been thought to be one of the major risk factors for the development of CVD. Less is known about the possible influence of fats from various sources on haemorheological abnormalities, which are considered an important factor in the pathogenesis of these diseases. The goal of the present study was to investigate effects of high-fat diets enriched in unsaturated fatty acids (USFA), SFA or trans-fatty acids (TFA), respectively, on haemorheological parameters in rats. Wistar female rats were divided into four groups and fed diets based on the AIN-93M formulation containing approximately 10% energy from soyabean oil (control group) or 40% energy from soyabean oil (USFA), palm oil (SFA) and vegetable shortening (TFA) for 8 weeks. The results showed that rats fed high-fat diets exhibited significant increases in serum TAG levels (P
| Original language | English |
|---|---|
| Pages (from-to) | 977-983 |
| Number of pages | 7 |
| Journal | British Journal of Nutrition |
| Volume | 103 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Apr 2010 |
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Keywords
- Blood viscosity
- Erythrocyte aggregation
- Erythrocyte deformability
- Free radicals
- High fat intake
- Plasma viscosity
- SFA
- Trans-fatty acids
- Unsaturated fatty acids
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics
- Medicine(all)
Cite this
Differential effect of high dietary fat intakes on haemorheological parameters in rats. / Tai, Cheng Jeng; Chen, Chao Hsiang; Chen, Hui Hsin; Liang, Hong Jen.
In: British Journal of Nutrition, Vol. 103, No. 7, 04.2010, p. 977-983.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differential effect of high dietary fat intakes on haemorheological parameters in rats
AU - Tai, Cheng Jeng
AU - Chen, Chao Hsiang
AU - Chen, Hui Hsin
AU - Liang, Hong Jen
PY - 2010/4
Y1 - 2010/4
N2 - High dietary intake of fats has been thought to be one of the major risk factors for the development of CVD. Less is known about the possible influence of fats from various sources on haemorheological abnormalities, which are considered an important factor in the pathogenesis of these diseases. The goal of the present study was to investigate effects of high-fat diets enriched in unsaturated fatty acids (USFA), SFA or trans-fatty acids (TFA), respectively, on haemorheological parameters in rats. Wistar female rats were divided into four groups and fed diets based on the AIN-93M formulation containing approximately 10% energy from soyabean oil (control group) or 40% energy from soyabean oil (USFA), palm oil (SFA) and vegetable shortening (TFA) for 8 weeks. The results showed that rats fed high-fat diets exhibited significant increases in serum TAG levels (P
AB - High dietary intake of fats has been thought to be one of the major risk factors for the development of CVD. Less is known about the possible influence of fats from various sources on haemorheological abnormalities, which are considered an important factor in the pathogenesis of these diseases. The goal of the present study was to investigate effects of high-fat diets enriched in unsaturated fatty acids (USFA), SFA or trans-fatty acids (TFA), respectively, on haemorheological parameters in rats. Wistar female rats were divided into four groups and fed diets based on the AIN-93M formulation containing approximately 10% energy from soyabean oil (control group) or 40% energy from soyabean oil (USFA), palm oil (SFA) and vegetable shortening (TFA) for 8 weeks. The results showed that rats fed high-fat diets exhibited significant increases in serum TAG levels (P
KW - Blood viscosity
KW - Erythrocyte aggregation
KW - Erythrocyte deformability
KW - Free radicals
KW - High fat intake
KW - Plasma viscosity
KW - SFA
KW - Trans-fatty acids
KW - Unsaturated fatty acids
UR - http://www.scopus.com/inward/record.url?scp=77951241059&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77951241059&partnerID=8YFLogxK
U2 - 10.1017/S0007114509992704
DO - 10.1017/S0007114509992704
M3 - Article
C2 - 19943983
AN - SCOPUS:77951241059
VL - 103
SP - 977
EP - 983
JO - British Journal of Nutrition
JF - British Journal of Nutrition
SN - 0007-1145
IS - 7
ER -