Different duration of high-altitude pre-exposure associated with the incidence of acute mountain sickness on Jade Mountain

Yi Ming Weng, Yu Hui Chiu, Jiun Jen Lynn, Wen Cheng Li, Shih Hao Wang, Wei Fong Kao, Tai Yi Hsu, Te Fa Chiu, Yu Jr Lin, Chang Wei Chan

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective The objective of this study is to determine the association between the duration of high-altitude (> 3000 m) pre-exposure and acute mountain sickness (AMS) incidence. Methods A prospective observational study was conducted on 2 random days each month from April 2007 to March 2008 at Paiyun Lodge (3402 m), Jade Mountain, Taiwan. Demographic data, prior AMS history, symptoms, and scores and the days and times of high-altitude pre-exposure within the preceding 2 months were obtained from lowland (<1500 m) trekkers. Results Totally, 1010 questionnaires were analyzed; 106, 76, and 828 trekkers had pre-exposure lasting at least 3 days (group 1), less than 3 days (group 2), and 0 days (group 3), respectively. Acute mountain sickness incidence was significantly higher in groups 2 and 3 than in group 1 (21.70%, 35.53%, 37.08%, respectively; P =.008). Logistic regression analysis indicated a significantly lower AMS risk in group 1 (group 1, P =.004; odds ratio [OR], 0.479; 95% confidence interval [CI], 0.290-0.791; group 2, P =.226; OR, 0.725; 95% CI, 0.430-1.221). In group 1, 28 and 78 trekkers had single and intermittent multiple pre-exposure, respectively. There was no difference in the incidence or severity of AMS symptoms between single and intermittent multiple pre-exposure (AMS, P =.838; headache, P =.891; dizziness or lightheadedness, P =.414; fatigue and/or weakness, P =.957; gastrointestinal symptoms, P =.257; difficulty sleeping, P =.804; AMS score, P =.796). Conclusions High-altitude pre-exposure lasting at least 3 days within the preceding 2 months was associated with a significant lower AMS incidence during a subsequent ascent among Jade Mountain trekkers.

Original languageEnglish
Pages (from-to)1113-1117
Number of pages5
JournalAmerican Journal of Emergency Medicine
Volume31
Issue number7
DOIs
Publication statusPublished - Jul 2013

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Altitude Sickness
Incidence
Dizziness
Odds Ratio
Confidence Intervals
Taiwan
Observational Studies
Fatigue
Headache
Logistic Models
History
Regression Analysis
Demography
Prospective Studies

ASJC Scopus subject areas

  • Emergency Medicine

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Different duration of high-altitude pre-exposure associated with the incidence of acute mountain sickness on Jade Mountain. / Weng, Yi Ming; Chiu, Yu Hui; Lynn, Jiun Jen; Li, Wen Cheng; Wang, Shih Hao; Kao, Wei Fong; Hsu, Tai Yi; Chiu, Te Fa; Lin, Yu Jr; Chan, Chang Wei.

In: American Journal of Emergency Medicine, Vol. 31, No. 7, 07.2013, p. 1113-1117.

Research output: Contribution to journalArticle

Weng, YM, Chiu, YH, Lynn, JJ, Li, WC, Wang, SH, Kao, WF, Hsu, TY, Chiu, TF, Lin, YJ & Chan, CW 2013, 'Different duration of high-altitude pre-exposure associated with the incidence of acute mountain sickness on Jade Mountain', American Journal of Emergency Medicine, vol. 31, no. 7, pp. 1113-1117. https://doi.org/10.1016/j.ajem.2013.03.028
Weng, Yi Ming ; Chiu, Yu Hui ; Lynn, Jiun Jen ; Li, Wen Cheng ; Wang, Shih Hao ; Kao, Wei Fong ; Hsu, Tai Yi ; Chiu, Te Fa ; Lin, Yu Jr ; Chan, Chang Wei. / Different duration of high-altitude pre-exposure associated with the incidence of acute mountain sickness on Jade Mountain. In: American Journal of Emergency Medicine. 2013 ; Vol. 31, No. 7. pp. 1113-1117.
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abstract = "Objective The objective of this study is to determine the association between the duration of high-altitude (> 3000 m) pre-exposure and acute mountain sickness (AMS) incidence. Methods A prospective observational study was conducted on 2 random days each month from April 2007 to March 2008 at Paiyun Lodge (3402 m), Jade Mountain, Taiwan. Demographic data, prior AMS history, symptoms, and scores and the days and times of high-altitude pre-exposure within the preceding 2 months were obtained from lowland (<1500 m) trekkers. Results Totally, 1010 questionnaires were analyzed; 106, 76, and 828 trekkers had pre-exposure lasting at least 3 days (group 1), less than 3 days (group 2), and 0 days (group 3), respectively. Acute mountain sickness incidence was significantly higher in groups 2 and 3 than in group 1 (21.70{\%}, 35.53{\%}, 37.08{\%}, respectively; P =.008). Logistic regression analysis indicated a significantly lower AMS risk in group 1 (group 1, P =.004; odds ratio [OR], 0.479; 95{\%} confidence interval [CI], 0.290-0.791; group 2, P =.226; OR, 0.725; 95{\%} CI, 0.430-1.221). In group 1, 28 and 78 trekkers had single and intermittent multiple pre-exposure, respectively. There was no difference in the incidence or severity of AMS symptoms between single and intermittent multiple pre-exposure (AMS, P =.838; headache, P =.891; dizziness or lightheadedness, P =.414; fatigue and/or weakness, P =.957; gastrointestinal symptoms, P =.257; difficulty sleeping, P =.804; AMS score, P =.796). Conclusions High-altitude pre-exposure lasting at least 3 days within the preceding 2 months was associated with a significant lower AMS incidence during a subsequent ascent among Jade Mountain trekkers.",
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T1 - Different duration of high-altitude pre-exposure associated with the incidence of acute mountain sickness on Jade Mountain

AU - Weng, Yi Ming

AU - Chiu, Yu Hui

AU - Lynn, Jiun Jen

AU - Li, Wen Cheng

AU - Wang, Shih Hao

AU - Kao, Wei Fong

AU - Hsu, Tai Yi

AU - Chiu, Te Fa

AU - Lin, Yu Jr

AU - Chan, Chang Wei

PY - 2013/7

Y1 - 2013/7

N2 - Objective The objective of this study is to determine the association between the duration of high-altitude (> 3000 m) pre-exposure and acute mountain sickness (AMS) incidence. Methods A prospective observational study was conducted on 2 random days each month from April 2007 to March 2008 at Paiyun Lodge (3402 m), Jade Mountain, Taiwan. Demographic data, prior AMS history, symptoms, and scores and the days and times of high-altitude pre-exposure within the preceding 2 months were obtained from lowland (<1500 m) trekkers. Results Totally, 1010 questionnaires were analyzed; 106, 76, and 828 trekkers had pre-exposure lasting at least 3 days (group 1), less than 3 days (group 2), and 0 days (group 3), respectively. Acute mountain sickness incidence was significantly higher in groups 2 and 3 than in group 1 (21.70%, 35.53%, 37.08%, respectively; P =.008). Logistic regression analysis indicated a significantly lower AMS risk in group 1 (group 1, P =.004; odds ratio [OR], 0.479; 95% confidence interval [CI], 0.290-0.791; group 2, P =.226; OR, 0.725; 95% CI, 0.430-1.221). In group 1, 28 and 78 trekkers had single and intermittent multiple pre-exposure, respectively. There was no difference in the incidence or severity of AMS symptoms between single and intermittent multiple pre-exposure (AMS, P =.838; headache, P =.891; dizziness or lightheadedness, P =.414; fatigue and/or weakness, P =.957; gastrointestinal symptoms, P =.257; difficulty sleeping, P =.804; AMS score, P =.796). Conclusions High-altitude pre-exposure lasting at least 3 days within the preceding 2 months was associated with a significant lower AMS incidence during a subsequent ascent among Jade Mountain trekkers.

AB - Objective The objective of this study is to determine the association between the duration of high-altitude (> 3000 m) pre-exposure and acute mountain sickness (AMS) incidence. Methods A prospective observational study was conducted on 2 random days each month from April 2007 to March 2008 at Paiyun Lodge (3402 m), Jade Mountain, Taiwan. Demographic data, prior AMS history, symptoms, and scores and the days and times of high-altitude pre-exposure within the preceding 2 months were obtained from lowland (<1500 m) trekkers. Results Totally, 1010 questionnaires were analyzed; 106, 76, and 828 trekkers had pre-exposure lasting at least 3 days (group 1), less than 3 days (group 2), and 0 days (group 3), respectively. Acute mountain sickness incidence was significantly higher in groups 2 and 3 than in group 1 (21.70%, 35.53%, 37.08%, respectively; P =.008). Logistic regression analysis indicated a significantly lower AMS risk in group 1 (group 1, P =.004; odds ratio [OR], 0.479; 95% confidence interval [CI], 0.290-0.791; group 2, P =.226; OR, 0.725; 95% CI, 0.430-1.221). In group 1, 28 and 78 trekkers had single and intermittent multiple pre-exposure, respectively. There was no difference in the incidence or severity of AMS symptoms between single and intermittent multiple pre-exposure (AMS, P =.838; headache, P =.891; dizziness or lightheadedness, P =.414; fatigue and/or weakness, P =.957; gastrointestinal symptoms, P =.257; difficulty sleeping, P =.804; AMS score, P =.796). Conclusions High-altitude pre-exposure lasting at least 3 days within the preceding 2 months was associated with a significant lower AMS incidence during a subsequent ascent among Jade Mountain trekkers.

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