Differences in factors influencing the familial aggregation of febrile convulsion in population and hospital patients

J. J. Tsai, M. C. Huang, F. W. Lung, C. C. Huang, Y. C. Chang

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Socio-demographic data, initial clinical manifestations, outcome and family aggregation of febrile convulsion (FC) were compared between 85 population and 364 multicenter patients. More patients presented with clustering of seizures and had recurrence of FC in multicenter group than in population group. Multicenter patients had more fever episodes per year, more day-care attendance and a higher incidence of FC history in their parents. The odds ratio of FC in the siblings was 6:1 in population group and 12:1 in multicenter group. Lower socioeconomic status influenced the presence of FC in the sibling of population group. Instead, FC histories in the father and paternal cousins of probands had influence on the presence of FC in the siblings of multicenter group. We conclude that the population FC sample rather than the hospital sample is the more representative. And there are differences not only in the clinical manifestations but also in the effect of environmental and genetic influences on the family aggregation in population and hospital patients.

Original languageEnglish
Pages (from-to)314-319
Number of pages6
JournalActa Neurologica Scandinavica
Volume94
Issue number5
Publication statusPublished - 1996
Externally publishedYes

Fingerprint

Febrile Seizures
Population
Population Groups
Siblings
Social Class
Fathers
Cluster Analysis
Seizures
Fever
Parents
Odds Ratio
Demography
Recurrence
Incidence

Keywords

  • Familiar aggregation
  • Febrile convulsion
  • Hospital
  • Population

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Differences in factors influencing the familial aggregation of febrile convulsion in population and hospital patients. / Tsai, J. J.; Huang, M. C.; Lung, F. W.; Huang, C. C.; Chang, Y. C.

In: Acta Neurologica Scandinavica, Vol. 94, No. 5, 1996, p. 314-319.

Research output: Contribution to journalArticle

@article{3a6bfb6e48714932b921bb12fbdf9783,
title = "Differences in factors influencing the familial aggregation of febrile convulsion in population and hospital patients",
abstract = "Socio-demographic data, initial clinical manifestations, outcome and family aggregation of febrile convulsion (FC) were compared between 85 population and 364 multicenter patients. More patients presented with clustering of seizures and had recurrence of FC in multicenter group than in population group. Multicenter patients had more fever episodes per year, more day-care attendance and a higher incidence of FC history in their parents. The odds ratio of FC in the siblings was 6:1 in population group and 12:1 in multicenter group. Lower socioeconomic status influenced the presence of FC in the sibling of population group. Instead, FC histories in the father and paternal cousins of probands had influence on the presence of FC in the siblings of multicenter group. We conclude that the population FC sample rather than the hospital sample is the more representative. And there are differences not only in the clinical manifestations but also in the effect of environmental and genetic influences on the family aggregation in population and hospital patients.",
keywords = "Familiar aggregation, Febrile convulsion, Hospital, Population",
author = "Tsai, {J. J.} and Huang, {M. C.} and Lung, {F. W.} and Huang, {C. C.} and Chang, {Y. C.}",
year = "1996",
language = "English",
volume = "94",
pages = "314--319",
journal = "Acta Neurologica Scandinavica",
issn = "0001-6314",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Differences in factors influencing the familial aggregation of febrile convulsion in population and hospital patients

AU - Tsai, J. J.

AU - Huang, M. C.

AU - Lung, F. W.

AU - Huang, C. C.

AU - Chang, Y. C.

PY - 1996

Y1 - 1996

N2 - Socio-demographic data, initial clinical manifestations, outcome and family aggregation of febrile convulsion (FC) were compared between 85 population and 364 multicenter patients. More patients presented with clustering of seizures and had recurrence of FC in multicenter group than in population group. Multicenter patients had more fever episodes per year, more day-care attendance and a higher incidence of FC history in their parents. The odds ratio of FC in the siblings was 6:1 in population group and 12:1 in multicenter group. Lower socioeconomic status influenced the presence of FC in the sibling of population group. Instead, FC histories in the father and paternal cousins of probands had influence on the presence of FC in the siblings of multicenter group. We conclude that the population FC sample rather than the hospital sample is the more representative. And there are differences not only in the clinical manifestations but also in the effect of environmental and genetic influences on the family aggregation in population and hospital patients.

AB - Socio-demographic data, initial clinical manifestations, outcome and family aggregation of febrile convulsion (FC) were compared between 85 population and 364 multicenter patients. More patients presented with clustering of seizures and had recurrence of FC in multicenter group than in population group. Multicenter patients had more fever episodes per year, more day-care attendance and a higher incidence of FC history in their parents. The odds ratio of FC in the siblings was 6:1 in population group and 12:1 in multicenter group. Lower socioeconomic status influenced the presence of FC in the sibling of population group. Instead, FC histories in the father and paternal cousins of probands had influence on the presence of FC in the siblings of multicenter group. We conclude that the population FC sample rather than the hospital sample is the more representative. And there are differences not only in the clinical manifestations but also in the effect of environmental and genetic influences on the family aggregation in population and hospital patients.

KW - Familiar aggregation

KW - Febrile convulsion

KW - Hospital

KW - Population

UR - http://www.scopus.com/inward/record.url?scp=0029801599&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029801599&partnerID=8YFLogxK

M3 - Article

VL - 94

SP - 314

EP - 319

JO - Acta Neurologica Scandinavica

JF - Acta Neurologica Scandinavica

SN - 0001-6314

IS - 5

ER -