Dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS) compared with women with non-PCOS-related infertility

Ya Hui Tsai, Ting Wen Wang, Hsiao Jui Wei, Chien-Yeh Hsu, Hsin Jung Ho, Wen Hua Chen, Robert Young, Chian Mey Liaw, Jane C J Chao

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The present study investigated dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS). A total of forty-five women (aged 25-40 years) with PCOS and 161 control women (aged 25-43 years) with non-PCOS-related infertility were recruited. Anthropometry, glucose tolerance and sex hormones were determined and dietary intake was assessed. Women with PCOS had lower serum sex hormone-binding globulin and increased BMI, waist:hip ratio, luteinising hormone, ratio of luteinising hormone:follicle-stimulating hormone, testosterone and free androgen index (FAI). Postprandial glucose, fasting insulin and insulin resistance were elevated in women with PCOS. Women with PCOS had reduced energy and carbohydrate intake but higher fat intake. Serum sex hormone-binding globulin level was negatively associated with BMI in both groups and negatively correlated with macronutrient intake in the PCOS group with hyperandrogenism. However, FAI was positively correlated with BMI, waist circumference and glucose metabolic parameters in both groups. Therefore, women with PCOS consume lower energy and carbohydrate compared with those with non-PCOS-related infertility and macronutrient intake is only negatively associated with serum sex hormone-binding globulin level in the PCOS group with hyperandrogenism.

Original languageEnglish
Pages (from-to)2190-2198
Number of pages9
JournalBritish Journal of Nutrition
Volume109
Issue number12
DOIs
Publication statusPublished - Jun 28 2013

Fingerprint

Polycystic Ovary Syndrome
Gonadal Steroid Hormones
Infertility
Ovary
Glucose
Serum Globulins
Sex Hormone-Binding Globulin
Hyperandrogenism
Luteinizing Hormone
Androgens
Carbohydrates
Anthropometry
Waist-Hip Ratio
Follicle Stimulating Hormone
Waist Circumference
Energy Intake
Insulin Resistance
Testosterone
Fasting
Fats

Keywords

  • Dietary intake
  • Glucose metabolism
  • Polycystic ovary syndrome
  • Sex hormones

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS) compared with women with non-PCOS-related infertility. / Tsai, Ya Hui; Wang, Ting Wen; Wei, Hsiao Jui; Hsu, Chien-Yeh; Ho, Hsin Jung; Chen, Wen Hua; Young, Robert; Liaw, Chian Mey; Chao, Jane C J.

In: British Journal of Nutrition, Vol. 109, No. 12, 28.06.2013, p. 2190-2198.

Research output: Contribution to journalArticle

Tsai, Ya Hui ; Wang, Ting Wen ; Wei, Hsiao Jui ; Hsu, Chien-Yeh ; Ho, Hsin Jung ; Chen, Wen Hua ; Young, Robert ; Liaw, Chian Mey ; Chao, Jane C J. / Dietary intake, glucose metabolism and sex hormones in women with polycystic ovary syndrome (PCOS) compared with women with non-PCOS-related infertility. In: British Journal of Nutrition. 2013 ; Vol. 109, No. 12. pp. 2190-2198.
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