Dicentric Ph1 chromosome

J. Whang Peng, T. A. Knutsen, E. C. Lee

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Five cases in a chronic myelogenous leukemia series were originally categorized as Ph1 positive and later developed another variant of the Ph1 chromosome. With the new Giemsa banding technique, it appeared to be a dicentric Ph1 chromosome. This chromosome was first noted 23 mth after diagnosis, with the latest appearance at 57 mth. Survival in 3 of the 5 patients after the appearance of the dicentric Ph1 chromosome was 6, 16, and 35 mth; the other 2 are still alive.

Original languageEnglish
Pages (from-to)2009-2012
Number of pages4
JournalJournal of the National Cancer Institute
Volume51
Issue number6
DOIs
Publication statusPublished - Jan 1 1973
Externally publishedYes

Fingerprint

Philadelphia Chromosome
Chromosomes, Human, Pair 6
Delayed Diagnosis
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Chromosomes
Survival

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Dicentric Ph1 chromosome. / Whang Peng, J.; Knutsen, T. A.; Lee, E. C.

In: Journal of the National Cancer Institute, Vol. 51, No. 6, 01.01.1973, p. 2009-2012.

Research output: Contribution to journalArticle

Whang Peng, J. ; Knutsen, T. A. ; Lee, E. C. / Dicentric Ph1 chromosome. In: Journal of the National Cancer Institute. 1973 ; Vol. 51, No. 6. pp. 2009-2012.
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