Diagnostic performance of 64-versus 256-slice computed tomography coronary angiography compared with conventional coronary angiography in patients with suspected coronary artery disease

Su Kiat Chua, Huei Fong Hung, Jun Jack Cheng, Min Tsung Tseng, Wai Yip Law, Chu Jen Kuo, Chiung Zuan Chiu, Che Ming Chang, Shih Huang Lee, Huey Ming Lo, Sheng Chang Lin, Jer Young Liou, Kou Gi Shyu

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: The newer 256-slice computed tomography coronary angiography (CTCA) has the capability of improving diagnostic performance in the detection of obstructive coronary artery disease (CAD) compared to 64-slice CTCA. The aim of this study was to compare the diagnostic performance of 64- versus 256-slice CTCA in two similar populations. Methods: Our study included 120 consecutive patients who were referred for CTCA and subsequently underwent conventional coronary angiography (CCA). Sixty patients were studied by 64-slice CTCA, with the other 60 by 256-slice CTCA. We compared the technical characteristics and diagnostic performance of 64- and 256-slice CTCA for the detection of ≥ 50% stenosis of the coronary arteries on CCA. Results: The 256-slice CTCA had a shorter scanning time (4.4 ± 0.6 sec vs. 5.0 ± 0.7 sec, p <0.001) compared to 64-slice CTCA. The diagnostic accuracy rates of 256-slice CTCA based on patient analysis (97% vs. 83%, p <0.05), vessel analysis (95% vs. 85%, p <0.05), and segment analysis (94% vs. 88%, p <0.05) were significantly superior to those of 64-slice CTCA. The diagnostic accuracy rates of 64- and 256-slice CTCA were affected by the presence of stent (65% vs. 75%, respectively, p > 0.05) and severe calcifications (75% vs. 82%, respectively, p > 0.05). Conclusions: In two similar populations, 256-slice CTCA displayed superior diagnostic performance than 64-slice CTCA. However, the performance of 256-slide CTCA is affected in those segments that are severely calcified and/or stented.

Original languageEnglish
Pages (from-to)151-159
Number of pages9
JournalActa Cardiologica Sinica
Volume29
Issue number2
Publication statusPublished - Mar 2013

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Coronary Angiography
Coronary Artery Disease
Computed Tomography Angiography
Coronary Stenosis
Population

Keywords

  • 256-slice helical CTCA
  • 64-slice helical CTCA
  • Computed tomography coronary angiography (CTCA)
  • Conventional coronary angiography
  • Diagnostic performance

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Diagnostic performance of 64-versus 256-slice computed tomography coronary angiography compared with conventional coronary angiography in patients with suspected coronary artery disease. / Chua, Su Kiat; Hung, Huei Fong; Cheng, Jun Jack; Tseng, Min Tsung; Law, Wai Yip; Kuo, Chu Jen; Chiu, Chiung Zuan; Chang, Che Ming; Lee, Shih Huang; Lo, Huey Ming; Lin, Sheng Chang; Liou, Jer Young; Shyu, Kou Gi.

In: Acta Cardiologica Sinica, Vol. 29, No. 2, 03.2013, p. 151-159.

Research output: Contribution to journalArticle

Chua, SK, Hung, HF, Cheng, JJ, Tseng, MT, Law, WY, Kuo, CJ, Chiu, CZ, Chang, CM, Lee, SH, Lo, HM, Lin, SC, Liou, JY & Shyu, KG 2013, 'Diagnostic performance of 64-versus 256-slice computed tomography coronary angiography compared with conventional coronary angiography in patients with suspected coronary artery disease', Acta Cardiologica Sinica, vol. 29, no. 2, pp. 151-159.
Chua, Su Kiat ; Hung, Huei Fong ; Cheng, Jun Jack ; Tseng, Min Tsung ; Law, Wai Yip ; Kuo, Chu Jen ; Chiu, Chiung Zuan ; Chang, Che Ming ; Lee, Shih Huang ; Lo, Huey Ming ; Lin, Sheng Chang ; Liou, Jer Young ; Shyu, Kou Gi. / Diagnostic performance of 64-versus 256-slice computed tomography coronary angiography compared with conventional coronary angiography in patients with suspected coronary artery disease. In: Acta Cardiologica Sinica. 2013 ; Vol. 29, No. 2. pp. 151-159.
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abstract = "Purpose: The newer 256-slice computed tomography coronary angiography (CTCA) has the capability of improving diagnostic performance in the detection of obstructive coronary artery disease (CAD) compared to 64-slice CTCA. The aim of this study was to compare the diagnostic performance of 64- versus 256-slice CTCA in two similar populations. Methods: Our study included 120 consecutive patients who were referred for CTCA and subsequently underwent conventional coronary angiography (CCA). Sixty patients were studied by 64-slice CTCA, with the other 60 by 256-slice CTCA. We compared the technical characteristics and diagnostic performance of 64- and 256-slice CTCA for the detection of ≥ 50{\%} stenosis of the coronary arteries on CCA. Results: The 256-slice CTCA had a shorter scanning time (4.4 ± 0.6 sec vs. 5.0 ± 0.7 sec, p <0.001) compared to 64-slice CTCA. The diagnostic accuracy rates of 256-slice CTCA based on patient analysis (97{\%} vs. 83{\%}, p <0.05), vessel analysis (95{\%} vs. 85{\%}, p <0.05), and segment analysis (94{\%} vs. 88{\%}, p <0.05) were significantly superior to those of 64-slice CTCA. The diagnostic accuracy rates of 64- and 256-slice CTCA were affected by the presence of stent (65{\%} vs. 75{\%}, respectively, p > 0.05) and severe calcifications (75{\%} vs. 82{\%}, respectively, p > 0.05). Conclusions: In two similar populations, 256-slice CTCA displayed superior diagnostic performance than 64-slice CTCA. However, the performance of 256-slide CTCA is affected in those segments that are severely calcified and/or stented.",
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AU - Hung, Huei Fong

AU - Cheng, Jun Jack

AU - Tseng, Min Tsung

AU - Law, Wai Yip

AU - Kuo, Chu Jen

AU - Chiu, Chiung Zuan

AU - Chang, Che Ming

AU - Lee, Shih Huang

AU - Lo, Huey Ming

AU - Lin, Sheng Chang

AU - Liou, Jer Young

AU - Shyu, Kou Gi

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N2 - Purpose: The newer 256-slice computed tomography coronary angiography (CTCA) has the capability of improving diagnostic performance in the detection of obstructive coronary artery disease (CAD) compared to 64-slice CTCA. The aim of this study was to compare the diagnostic performance of 64- versus 256-slice CTCA in two similar populations. Methods: Our study included 120 consecutive patients who were referred for CTCA and subsequently underwent conventional coronary angiography (CCA). Sixty patients were studied by 64-slice CTCA, with the other 60 by 256-slice CTCA. We compared the technical characteristics and diagnostic performance of 64- and 256-slice CTCA for the detection of ≥ 50% stenosis of the coronary arteries on CCA. Results: The 256-slice CTCA had a shorter scanning time (4.4 ± 0.6 sec vs. 5.0 ± 0.7 sec, p <0.001) compared to 64-slice CTCA. The diagnostic accuracy rates of 256-slice CTCA based on patient analysis (97% vs. 83%, p <0.05), vessel analysis (95% vs. 85%, p <0.05), and segment analysis (94% vs. 88%, p <0.05) were significantly superior to those of 64-slice CTCA. The diagnostic accuracy rates of 64- and 256-slice CTCA were affected by the presence of stent (65% vs. 75%, respectively, p > 0.05) and severe calcifications (75% vs. 82%, respectively, p > 0.05). Conclusions: In two similar populations, 256-slice CTCA displayed superior diagnostic performance than 64-slice CTCA. However, the performance of 256-slide CTCA is affected in those segments that are severely calcified and/or stented.

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KW - 64-slice helical CTCA

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KW - Conventional coronary angiography

KW - Diagnostic performance

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