Diagnosis of disseminated candidiasis by fine needle aspiration of lymph node and by splenic imprint in a patient with acute promyelocytic leukemia

Tsu Yi Chao, Jang Yang Chang, Chih Yung Yu, Tang Yi Tsao

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Cytologic studies were done on fine needle aspirates of the lymph node and imprints of splenic biopsies from a patient with acute promyelocytic leukemia who was febrile while being treated with chemotherapy. Examination of the lymph node aspirates revealed pus and numerous pseudohyphae which were later identified as Candida tropicalis. When multiple nodular lesions were detected in the spleen by abdominal sonography and CT scan, needle biopsy of the spleen was done. Cytologic examination of touch imprints of the biopsy disclosed intracellular fungal blastospores. The patient was treated with and responded well to amphotericin B and 5-fluorocytosine. As a result of our experience with this patient we emphasize the importance of close incorporation of clinical information and diagnostic cytology. With such a cooperation, cytologic studies become a most useful method for diagnosis.

Original languageEnglish
Pages (from-to)148-151
Number of pages4
JournalActa Haematologica
Volume94
Issue number3
DOIs
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Acute Promyelocytic Leukemia
Candidiasis
Fine Needle Biopsy
Lymph Nodes
Spleen
Candida tropicalis
Biopsy
Flucytosine
Suppuration
Touch
Needle Biopsy
Amphotericin B
Needles
Cell Biology
Ultrasonography
Fever
Drug Therapy

Keywords

  • Candidiasis, disseminated
  • Fine needle aspiration cytology
  • Leukemia, acute promyelocytic

ASJC Scopus subject areas

  • Hematology

Cite this

Diagnosis of disseminated candidiasis by fine needle aspiration of lymph node and by splenic imprint in a patient with acute promyelocytic leukemia. / Chao, Tsu Yi; Chang, Jang Yang; Yu, Chih Yung; Tsao, Tang Yi.

In: Acta Haematologica, Vol. 94, No. 3, 1995, p. 148-151.

Research output: Contribution to journalArticle

@article{1de7fed4a41640d2ae3d92a38e6581ed,
title = "Diagnosis of disseminated candidiasis by fine needle aspiration of lymph node and by splenic imprint in a patient with acute promyelocytic leukemia",
abstract = "Cytologic studies were done on fine needle aspirates of the lymph node and imprints of splenic biopsies from a patient with acute promyelocytic leukemia who was febrile while being treated with chemotherapy. Examination of the lymph node aspirates revealed pus and numerous pseudohyphae which were later identified as Candida tropicalis. When multiple nodular lesions were detected in the spleen by abdominal sonography and CT scan, needle biopsy of the spleen was done. Cytologic examination of touch imprints of the biopsy disclosed intracellular fungal blastospores. The patient was treated with and responded well to amphotericin B and 5-fluorocytosine. As a result of our experience with this patient we emphasize the importance of close incorporation of clinical information and diagnostic cytology. With such a cooperation, cytologic studies become a most useful method for diagnosis.",
keywords = "Candidiasis, disseminated, Fine needle aspiration cytology, Leukemia, acute promyelocytic",
author = "Chao, {Tsu Yi} and Chang, {Jang Yang} and Yu, {Chih Yung} and Tsao, {Tang Yi}",
year = "1995",
doi = "10.1159/000203999",
language = "English",
volume = "94",
pages = "148--151",
journal = "Acta Haematologica",
issn = "0001-5792",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Diagnosis of disseminated candidiasis by fine needle aspiration of lymph node and by splenic imprint in a patient with acute promyelocytic leukemia

AU - Chao, Tsu Yi

AU - Chang, Jang Yang

AU - Yu, Chih Yung

AU - Tsao, Tang Yi

PY - 1995

Y1 - 1995

N2 - Cytologic studies were done on fine needle aspirates of the lymph node and imprints of splenic biopsies from a patient with acute promyelocytic leukemia who was febrile while being treated with chemotherapy. Examination of the lymph node aspirates revealed pus and numerous pseudohyphae which were later identified as Candida tropicalis. When multiple nodular lesions were detected in the spleen by abdominal sonography and CT scan, needle biopsy of the spleen was done. Cytologic examination of touch imprints of the biopsy disclosed intracellular fungal blastospores. The patient was treated with and responded well to amphotericin B and 5-fluorocytosine. As a result of our experience with this patient we emphasize the importance of close incorporation of clinical information and diagnostic cytology. With such a cooperation, cytologic studies become a most useful method for diagnosis.

AB - Cytologic studies were done on fine needle aspirates of the lymph node and imprints of splenic biopsies from a patient with acute promyelocytic leukemia who was febrile while being treated with chemotherapy. Examination of the lymph node aspirates revealed pus and numerous pseudohyphae which were later identified as Candida tropicalis. When multiple nodular lesions were detected in the spleen by abdominal sonography and CT scan, needle biopsy of the spleen was done. Cytologic examination of touch imprints of the biopsy disclosed intracellular fungal blastospores. The patient was treated with and responded well to amphotericin B and 5-fluorocytosine. As a result of our experience with this patient we emphasize the importance of close incorporation of clinical information and diagnostic cytology. With such a cooperation, cytologic studies become a most useful method for diagnosis.

KW - Candidiasis, disseminated

KW - Fine needle aspiration cytology

KW - Leukemia, acute promyelocytic

UR - http://www.scopus.com/inward/record.url?scp=0028842872&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028842872&partnerID=8YFLogxK

U2 - 10.1159/000203999

DO - 10.1159/000203999

M3 - Article

C2 - 7502633

AN - SCOPUS:0028842872

VL - 94

SP - 148

EP - 151

JO - Acta Haematologica

JF - Acta Haematologica

SN - 0001-5792

IS - 3

ER -