Abstract

Background: The purpose of this study was to investigate the relationship between perforated appendicitis and patient with diabetes using a population-based data set. Methods: This study used data from the Longitudinal Health Insurance Database 2005 in Taiwan. We identified 4,806 patients hospitalized with acute appendicitis. The independent variable was whether a patient had ever received a diagnosis of diabetes before the index hospitalization. We performed a conditional logistic regression model to explore the odds ratio and its corresponding 95% confidence interval of perforated appendicitis. Results: Rates of perforated appendicitis for patients with and those without diabetes were 46.2% and 28.3%, respectively. A chi-square test revealed that there was a significant difference in rates of perforated appendicitis between patients with and those without diabetes (P < .001). The conditional logistic regression model revealed that the adjusted odds ratio of perforated appendicitis for patients with diabetes was 1.35 (95% confidence interval = 1.11 to 1.65) compared with patients without diabetes. Conclusions: Our study demonstrated that a history of diabetes is an important factor with regard to the rate of perforated appendicitis.

Original languageEnglish
Pages (from-to)735-739
JournalAmerican Journal of Surgery
Volume212
Issue number4
DOIs
Publication statusPublished - Oct 1 2016

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Appendicitis
Population
Logistic Models
Odds Ratio
Confidence Intervals
Chi-Square Distribution
Health Insurance
Taiwan
Hospitalization
Databases

Keywords

  • Appendix
  • Diabetes
  • Perforated appendicitis

ASJC Scopus subject areas

  • Surgery

Cite this

Diabetes is associated with perforated appendicitis : Evidence from a population-based study. / Wei, Po Li; Lin, Herng Ching; Kao, Li Ting; Chen, Yi Hua; Lee, Cha Ze.

In: American Journal of Surgery, Vol. 212, No. 4, 01.10.2016, p. 735-739.

Research output: Contribution to journalArticle

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KW - Appendix

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KW - Perforated appendicitis

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