Diabetes is associated with drug-resistant tuberculosis in Eastern Taiwan

A. H. Hsu, J. J. Lee, C. Y. Chiang, Y. H. Li, L. K. Chen, C. B. Lin

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

We assessed the association between diabetes mellitus and drug-resistant tuberculosis (TB). Among new patients, diabetes was significantly associated with any resistance to isoniazid excluding multidrug-resistant TB (MDR-TB; adjusted OR [aOR] 1.88, 95%CI 1.07-3.31), but not with MDR-TB (aOR 0.95, 95%CI 0.34-2.68). Among previously treated patients, diabetes was also significantly associated with INH resistance (aOR 6.76, 95%CI 1.53-29.98) but not with MDR-TB (aOR 1.52, 95%CI 0.59-3.95). We concluded that diabetes was associated with INH resistance and speculated that the sample size of retreatment cases was insufficient to confirm the association between diabetes and MDR-TB.

Original languageEnglish
Pages (from-to)354-356
Number of pages3
JournalInternational Journal of Tuberculosis and Lung Disease
Volume17
Issue number3
DOIs
Publication statusPublished - Mar 1 2013

Keywords

  • Diabetes
  • Isoniazid resistance
  • Multidrug-resistant tuberculosis
  • Transmission

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Infectious Diseases

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