Development of polycaprolactone/hydroxyapatite composite resin for 405 nm digital light projection 3D printing

Yuan Min Lin, Hsuan Chen, Chih Hsin Lin, Pin Ju Huang, Shyh Yuan Lee

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Purpose: The purpose of this study is to develop resin composite materials composed of polycaprolactone (PCL) acrylates and hydroxyapatite (HA) nanoparticles for ultraviolet digital light projection (DLP) three-dimensional (3D) printing technique. Design/methodology/approach: Two PCL-based triacrylates, namely, glycerol-3 caprolactone-triacrylate (Gly-3CL-TA) and glycerol-6 caprolactone-triacrylate (Gly-6CL-TA) were synthesized from ring-opening polymerization of ε-caprolacton monomer in the presence of glycerol and then acrylation was performed using acryloyl chloride. 3D printing resins made of Gly-3CL-TA or Gly-6CL-TA, 5% HA and 3% of photoinitiator 2,4,6-Trimethylbenzoyl-diphenyl-phosphineoxide were then formulated. The surface topography, surface element composition, flexural strength, flexural modulus, cytotoxicity and degradation of the PCL-based scaffolds were then characterized. Findings: Resin composite composed of Gly-3CL-TA or Gly-6CL-TA and 5% (w/w) of HA can be printed by 405 nm DLP 3D printers. The former has lower viscosity and thus can form a more uniform layer-by-layer structure, while the latter exhibited a higher flexural strength and modulus after being printed. Both composite materials are non-cytotoxic and degradable. Originality/value: This study provides a direction of the formulation of environment-friendly resin composite for DLP 3D printing. Both resin composites have huge potential in tissue engineering applications.

Original languageEnglish
Pages (from-to)951-958
Number of pages8
JournalRapid Prototyping Journal
Issue number5
Publication statusAccepted/In press - Jan 1 2020
Externally publishedYes


  • 3D printing
  • Cytotoxicity
  • Hydroxyapatite
  • Polycaprolactone
  • Tissue engineering

ASJC Scopus subject areas

  • Mechanical Engineering
  • Industrial and Manufacturing Engineering


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