Detoxification of high-dose zolpidem using cross-titration with an adequate equivalent dose of diazepam

Shao Chien Chen, Hsi Chung Chen, Shih Cheng Liao, Mei Chih Meg Tseng, Ming Been Lee

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Background: There have been numerous case reports of zolpidem abuse and dependence in the recent decade, giving rise to a focus on adverse withdrawal events such as seizure. No standard detoxification regimen has been proposed to date, despite the similarity of effects of zolpidem and benzodiazepines at high doses. Case Descriptions: We describe the results, in a 53-year-old female patient, of undergoing three different zolpidem detoxification programs. Conclusions: Because of her experiences, we recommend using the cross-titration strategy with an adequate equivalent dose of diazepam.

Original languageEnglish
Pages (from-to)210.e5-210.e7
JournalGeneral Hospital Psychiatry
Volume34
Issue number2
DOIs
Publication statusPublished - Mar 2012

Keywords

  • Benzodiazepines
  • Detoxification
  • Diazepam
  • Withdrawal
  • Zolpidem

ASJC Scopus subject areas

  • Psychiatry and Mental health

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