Abstract
Objectives The primary objective of this study was to investigate the feasibility of using niosomes as a delivery vehicle for the dermal administration in vitro of black tea extract (BTE) as a sunscreen. Methods Multi-lamellar niosomes were obtained by means of a previously reported method of lipid hydration films. In vitro penetration experiments through nude mouse skin were carried out to evaluate the potential of niosomes as a dermal formulation. The nude mouse skin membrane allowed the effects of penetration with a niosome formulation to be evaluated. Penetration rates of caffeine- and gallic acid-loaded niosomes in a steady state were higher than dispersion in aqueous solutions. Results For skin permeation, higher transdermal absorption rates were seen with solutions of caffeine and gallic acid. Conclusions In the near future, BTE as a sunscreen agent will be dermally delivered by niosomes.
| Original language | English |
|---|---|
| Pages (from-to) | 239-245 |
| Number of pages | 7 |
| Journal | International Journal of Dermatology |
| Volume | 52 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2013 |
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ASJC Scopus subject areas
- Dermatology
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Dermal delivery by niosomes of black tea extract as a sunscreen agent. / Yeh, Meng I.; Huang, Hsiu Chin; Liaw, Jia Horng; Huang, Min Chuan; Huang, Kuei Fen; Hsu, Feng-Lin.
In: International Journal of Dermatology, Vol. 52, No. 2, 02.2013, p. 239-245.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dermal delivery by niosomes of black tea extract as a sunscreen agent
AU - Yeh, Meng I.
AU - Huang, Hsiu Chin
AU - Liaw, Jia Horng
AU - Huang, Min Chuan
AU - Huang, Kuei Fen
AU - Hsu, Feng-Lin
PY - 2013/2
Y1 - 2013/2
N2 - Objectives The primary objective of this study was to investigate the feasibility of using niosomes as a delivery vehicle for the dermal administration in vitro of black tea extract (BTE) as a sunscreen. Methods Multi-lamellar niosomes were obtained by means of a previously reported method of lipid hydration films. In vitro penetration experiments through nude mouse skin were carried out to evaluate the potential of niosomes as a dermal formulation. The nude mouse skin membrane allowed the effects of penetration with a niosome formulation to be evaluated. Penetration rates of caffeine- and gallic acid-loaded niosomes in a steady state were higher than dispersion in aqueous solutions. Results For skin permeation, higher transdermal absorption rates were seen with solutions of caffeine and gallic acid. Conclusions In the near future, BTE as a sunscreen agent will be dermally delivered by niosomes.
AB - Objectives The primary objective of this study was to investigate the feasibility of using niosomes as a delivery vehicle for the dermal administration in vitro of black tea extract (BTE) as a sunscreen. Methods Multi-lamellar niosomes were obtained by means of a previously reported method of lipid hydration films. In vitro penetration experiments through nude mouse skin were carried out to evaluate the potential of niosomes as a dermal formulation. The nude mouse skin membrane allowed the effects of penetration with a niosome formulation to be evaluated. Penetration rates of caffeine- and gallic acid-loaded niosomes in a steady state were higher than dispersion in aqueous solutions. Results For skin permeation, higher transdermal absorption rates were seen with solutions of caffeine and gallic acid. Conclusions In the near future, BTE as a sunscreen agent will be dermally delivered by niosomes.
UR - http://www.scopus.com/inward/record.url?scp=84873058883&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84873058883&partnerID=8YFLogxK
U2 - 10.1111/j.1365-4632.2012.05587.x
DO - 10.1111/j.1365-4632.2012.05587.x
M3 - Article
C2 - 22913389
AN - SCOPUS:84873058883
VL - 52
SP - 239
EP - 245
JO - International Journal of Dermatology
JF - International Journal of Dermatology
SN - 0011-9059
IS - 2
ER -